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995455 - Disclosure - Cybersecurity Risk Management, Strategy and Governance
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995457 - Disclosure - The Company
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995467 - Disclosure - Summary of Significant Accounting Policies
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995477 - Disclosure - Discontinued Operations
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995487 - Disclosure - Collaboration Agreements, License Agreement and Revenues
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995507 - Disclosure - Fair Value Measurements
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995547 - Disclosure - Liability Related to Sale of Future Revenues
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995587 - Disclosure - Net Loss Per Share
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995607 - Disclosure - Related Party Transactions
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995627 - Disclosure - Subsequent Event
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995637 - Disclosure - Schedule II - Valuation and Qualifying Accounts
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995647 - Disclosure - Summary of Significant Accounting Policies (Policies)
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995677 - Disclosure - Exclusive License and Option to Acquire Fortis Therapeutics (Tables)
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995807 - Disclosure - Summary of Significant Accounting Policies - Additional Information (Detail)
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995877 - Disclosure - Collaboration Agreements, License Agreement and Revenues - AstraZeneca Agreements - Additional Information 1 (Detail)
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995907 - Disclosure - Collaboration Agreements, License Agreement and Revenues - Summary of License Revenue and Development Revenue Recognized under Agreement (Detail)
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995977 - Disclosure - Collaboration Agreements, License Agreement and Revenues - Roll-forward of Related Contract Liabilities (Detail)
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995987 - Disclosure - Collaboration Agreements, License Agreement and Revenues - Drug Product Revenue - Summary of Drug Product Revenue (Detail)
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995997 - Disclosure - Collaboration Agreements, License Agreement and Revenues - Drug Product Revenue - Additional Information (Detail)
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996007 - Disclosure - Leases - Schedule of Maturities of Lease Liabilities (Detail) 2
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996017 - Disclosure - Collaboration Agreements, License Agreement and Revenues - Additional Information (Detail)
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996027 - Disclosure - Exclusive License and Option to Acquire Fortis Therapeutics - Schedule of Allocation of Purchase Consideration Based on Estimated Fair Values of Acquired Assets (Details)
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996047 - Disclosure - Equity method investment - Variable Interest Entity - Summary of Equity Method Investment (Detail)
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996057 - Disclosure - Fair Value Measurements - Fair Values of Financial Assets Measured on Recurring Basis (Detail)
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996067 - Disclosure - Fair Value Measurements - Additional Information (Detail)
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996077 - Disclosure - Leases - Additional Information (Detail)
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996087 - Disclosure - Leases - Schedule of Lease Assets and Related Lease Liabilities (Detail)
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996097 - Disclosure - Leases - Components of Lease Expense (Detail)
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996107 - Disclosure - Leases - Schedule of Lease Term and Discount Rate (Detail)
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996117 - Disclosure - Leases - Schedule of Supplemental Cash Flow Information Related to Leases (Detail)
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996127 - Disclosure - Leases - Schedule of Maturities of Lease Liabilities (Detail)
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996137 - Disclosure - Consolidated Variable Interest Entity - Fortis - Additional Information (Detail)
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996147 - Disclosure - Balance Sheet Components - Schedule of Cash and Cash Equivalents (Detail)
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996157 - Disclosure - Balance Sheet Components - Additional Information (Detail)
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996167 - Disclosure - Balance Sheet Components - Summary of Amortized Cost, Gross Unrealized Holding Gains or Losses, and Fair Value of Available-for-Sale Investments (Detail)
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996177 - Disclosure - Balance Sheet Components - Summary of Available for Sale Securities in Unrealized Loss Position, Fair Value and Gross Unrealized Loss By Length of Time Security in Continual Unrealized Loss Position (Detail)
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996187 - Disclosure - Balance Sheet Components - Schedule of Inventory (Detail)
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996197 - Disclosure - Balance Sheet Components - Schedule of Prepaid Expenses and Other Current Assets (Detail)
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996207 - Disclosure - Balance Sheet Components - Schedule of Property and Equipment (Detail)
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996217 - Disclosure - Balance Sheet Components - Schedule of Accrued and Other Current Liabilities (Detail)
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996227 - Disclosure - Balance Sheet Components - Schedule of Other Long-term Liabilities (Detail)
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996237 - Disclosure - Liability Related to Sale of Future Revenues - Additional Information (Detail)
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996247 - Disclosure - Liability Related to Sale of Future Revenues - Schedule of Activity of Liability Related to Sale of Future Revenues (Detail)
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996257 - Disclosure - Senior Secured Term Loan Facilities - Additional Information (Detail)
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996267 - Disclosure - Senior Secured Term Loan Facilities - Summary of Senior Secured Term Loan Facilities (Detail)
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996277 - Disclosure - Liability Related to Sale of Future Royalties - Schedule of Revenue Payment Cap Maturity (Details)
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996287 - Disclosure - Product Development Obligations - Additional Information (Detail)
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996297 - Disclosure - Commitments and Contingencies - Summary of Outstanding Non-cancelable Purchase Obligations (Detail)
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996307 - Disclosure - Commitments and Contingencies - Additional Information (Detail)
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996317 - Disclosure - Equity and Stock-based Compensation - Common Stock - Additional information (Detail)
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996327 - Disclosure - Equity and Stock-based Compensation - Summary of Common Stock Reserved for Future Issuance (Detail)
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996337 - Disclosure - Equity and Stock-based Compensation -At-the-Market Program-Additional Information (Details)
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996347 - Disclosure - Equity and Stock-based Compensation - Stock Plans - Additional information (Detail)
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996357 - Disclosure - Equity and Stock-based Compensation - Stock Plans - Summary of Stock Option Transactions (Detail)
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996367 - Disclosure - Equity and Stock-based Compensation - Summary of RSU,PRSU and TSR Awards (Detail)
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996377 - Disclosure - Equity and Stock-based Compensation - Employee Stock Purchase Plan - Additional information (Detail)
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996387 - Disclosure - Equity and Stock-based Compensation - Schedule of Recorded Stock-Based Compensation Expense (Detail)
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996397 - Disclosure - Equity and Stock-based Compensation - Schedule of Assumptions used to Estimate Fair Value of Stock Options Granted and Employee Stock Purchase Plans (Detail)
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996407 - Disclosure - Equity and Stock-based Compensation - Stock-Based Compensation - Additional information (Detail)
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996417 - Disclosure - Equity and Stock-based Compensation - Warrants - Additional information (Detail)
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996427 - Disclosure - Equity and Stock based compensation - Schedule of Assumptions used to Estimate Fair Value of TSR Awards (Details)
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996437 - Disclosure - Equity and Stock-based Compensation - Subsidiary Stock and Non-Controlling Interests - Additional information (Detail)
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996447 - Disclosure - Net Loss Per Share - Schedule of Weighted Impacts of Outstanding Anti-dilutive Securities Excluded from Calculation of Diluted Net Loss Per Share (Detail)
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996457 - Disclosure - Income Taxes - Components of Loss Before Income Taxes (Detail)
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996467 - Disclosure - Income Taxes - Schedule of Components of Provision For Income Taxes (Detail)
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996477 - Disclosure - Income Taxes - Schedule of Reconciliation Between Statutory Federal Income Tax Rate and Effective Tax Rate (Detail)
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996487 - Disclosure - Income Taxes - Schedule of Significant Components of Deferred Tax Assets (Detail)
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996497 - Disclosure - Income Taxes - Additional Information (Detail)
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996507 - Disclosure - Income Taxes - Reconciliation of the Beginning and Ending Amounts of Unrecognized Income Tax Benefits (Detail)
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996517 - Disclosure - Related Party Transactions - Additional Information (Detail)
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996527 - Disclosure - Segment and Geographic Information - Additional information (Detail)
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996537 - Disclosure - Segment and Geographic Information - Schedule of Revenue by Geographic Area (Detail)
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996547 - Disclosure - Segment and Geographic Information - Schedule of Customer Concentration by Collaboration Partners (Detail)
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996557 - Disclosure - Schedule II - Valuation and Qualifying Accounts (Detail)
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Statement [Line Items]
Statement [Line Items]
Debt Instrument, Interest Rate During Period
Interest rate per annum
Accounts Receivable from Distributors [Member]
Accounts Receivable From Distributors [Member]
Accounts receivable from distributors.
Debt Instrument [Axis]
Cybersecurity Risk Board of Directors Oversight [Text Block]
Warrants exercised, Shares
Warrant Exercised During Period Shares
Warrant exercised during period shares.
Transaction Type
Transaction Type [Axis]
Increase (Decrease) in Accounts Receivable
Accounts receivable, net
Plan Name
Plan Name [Domain]
Liability Related to Sale of Future Revenues
Liability Related To Sale Of Future Revenues [Policy Text Block]
Liability related to sale of future revenues.
Clinical and Development Milestone [Member]
Clinical Development Milestones [Member]
Clinical development milestone.
Less: Initial issuance costs
Initial Issuance Costs Related To Sale Of Future Revenues
Initial issuance costs related to sale of future revenues.
Valuation And Qualifying Accounts Disclosure [Table]
SEC Schedule, 12-09, Valuation and Qualifying Accounts Disclosure [Table]
Deferred revenue
Deferred Tax Assets, Deferred Income
Accrued and other liabilities from related party
Increase (Decrease) in Accounts Payable, Related Parties
API Shipment [Member]
A P I Shipment [Member]
API shipment.
Entity Address, Postal Zip Code
Entity Address, Postal Zip Code
HiFiBiO Agreement [Member]
Hi Fi Bi O Agreement [Member]
HiFiBiO agreement.
Loss Contingency, Receivable, Current
Litigation settlement receivable
Insurance proceeds receivable for litigation settlement
Astellas Agreement [Member]
Astellas Collaboration Agreement [Member]
Astellas agreements.
Astellas [Member]
Cybersecurity Risk Board Committee or Subcommittee Responsible for Oversight [Text Block]
Revenue during period from performance obligations
Revenue, Remaining Performance Obligation, Amount
Disposal Group Name [Axis]
Office Equipment [Member]
Office Equipment [Member]
Schedule of Lease Assets and Related Lease Liabilities
Schedule Of Lease Assets And Related Lease Liabilities Table [Text Block]
Schedule of lease assets and related lease liabilities.
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Table]
Fair Value, Recurring and Nonrecurring [Table]
Entity Incorporation, State or Country Code
Entity Incorporation, State or Country Code
Foreign net operating loss carryforwards
Deferred Tax Assets, Operating Loss Carryforwards, Foreign
Restructuring charge
Restructuring Charges, Total
Restructuring Charges
Restructuring plan, non-recurring charges
Total future lease payments
Finance Lease, Liability, to be Paid
Interest payments
Interest Paid, Excluding Capitalized Interest, Operating Activities
Income (Loss) from Continuing Operations before Equity Method Investments, Income Taxes, Noncontrolling Interest
Loss from continuing operations before income taxes
Non cash acquisition in Fortis
Non cash acquisition in Fortis
Unrecognized compensation costs
Share-Based Payment Arrangement, Nonvested Award, Excluding Option, Cost Not yet Recognized, Amount
Number of operating segment
Number of Operating Segments
First Anniversary [Member]
Share-Based Payment Arrangement, Tranche One [Member]
Exercisable, Weighted Average Exercise Price per Share
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Exercise Price
Balance, Shares
Balance, Shares
Shares, Outstanding
Description of payment term
Revenue, Performance Obligation, Description of Payment Terms
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Axis]
Schedule of Recognized Identified Assets Acquired and Liabilities Assumed [Table Text Block]
Schedule of Allocation of Purchase Consideration Based on Estimated Fair Values of Acquired Assets
Percentage of outstanding shares acquired
Business Acquisition, Percentage of Voting Interests Acquired
Auditor Name
Auditor Name
Federal
Deferred Federal Income Tax Expense (Benefit)
Accrued product development costs excluding interest
Accrued Product Development Costs Excluding Interest
Accrued Product Development Costs Excluding Interest.
Drug Product Revenue [Member]
Drug product revenue.
Drug Product Revenue, Net [Member]
Drug Product Revenue [Member]
Level 2 [Member]
Fair Value, Inputs, Level 2 [Member]
Share Based Compensation Arrangement By Share Based Payment Award [Line Items]
Share-Based Compensation Arrangement by Share-Based Payment Award [Line Items]
Beyond 2027
Revenue Payment Cap Amount Due After Year Five
Revenue payment cap amount due after year five.
Long-Term Debt, Type [Domain]
Recently Issued Accounting Guidance Not Yet Adopted
Recently Issued Accounting Guidance Not Yet Adopted Policy [Text Block]
Recently issued accounting guidance not yet adopted.
Purchase consideration
Business Combination, Consideration Transferred, Total
Business Combination, Consideration Transferred
Foreign statute of limitation generally remains open in the year
Open Tax Year
Shared development costs
Shared Development Costs
Represents the total amount of development costs that will be shared under collaborative agreement.
Current:
Current Federal, State and Local, Tax Expense (Benefit) [Abstract]
Depreciation Expense for Continuing Operations
Depreciation expense for continuing operations.
Depreciation expense for continuing operations
Transfers of assets into level 3
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset Transfers Into Level 3
Commitments and Contingencies
Commitments and Contingencies Disclosure [Text Block]
Disposal Group, Including Discontinued Operation, Cash Consideration
Disposal group, including discontinued operation, cash consideration.
Purchase price in cash
Biosynthetic Cornea.
Biosynthetic Cornea [Member]
Schedule Of Stock By Class [Table]
Stock, Class of Stock [Table]
Latest Tax Year [Member]
Latest Tax Year [Member]
Debt instrument accrued interest.
Debt Instrument Accrued Interest
Accrued interest
Japan [Member]
JAPAN
Product and Service
Product and Service [Axis]
Non-cash: Right-of-use assets obtained in exchange for new lease liabilities:
Non Cash Right Of Use Assets Obtained In Exchange For New Lease Liabilities [Abstract]
Non cash right of use assets obtained in exchange for new lease liabilities.
Delayed Draw Term Loan (DDTL) [Member]
Delayed Draw Term Loan [Member]
Schedule of Inventory by Geographic Area
Inventory By Geographic Areas Table [Text Block]
Inventory by geographic areas.
Finite-Lived Intangible Assets by Major Class
Finite-Lived Intangible Assets by Major Class [Axis]
Investment Income, Dividend
Dividend received
Dividend Received
Investment, Name [Domain]
Percentage of vesting rights
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights, Percentage
Unrestricted cash and cash equivalent balance maintain in accounts.
Unrestricted Cash And Cash Equivalent Balance Maintain In Accounts
Unrestricted cash and cash equivalent balance required to maintain in accounts
Commercial sales and other events milestone
Commercial Sales And Other Events Milestone
Commercial sales and other events milestone.
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Domain]
Number of common stock repurchased
Stock Repurchased During Period, Shares
Schedule Of Leases [Line Items]
Schedule Of Leases [Line Items]
Schedule of leases.
Cumulative Effect, Period of Adoption
Cumulative Effect, Period of Adoption [Domain]
Finance leases
Increase (Decrease) in Right of use Asset Obtained in Exchange for Finance Lease Liability.
Increase (decrease) in right-of-use asset obtained in exchange for finance lease liability.
ESPP [Member]
Employee Stock [Member]
Repayments of lease obligations
Repayments of Debt and Lease Obligation
Related Party Transaction [Line Items]
Related Party Transaction [Line Items]
API and bulk drug product price true-up
Accrued API and bulk drug product price true-up current
Accrued API and bulk drug product price true-up current.
Cybersecurity Risk Management Processes Integrated [Text Block]
Percentage of Accounts Receivable [Member]
Concentration Risk Benchmark
Concentration Risk Benchmark [Axis]
Series H [Member]
Series H Preferred Stock [Member]
Number of identified performance obligation at inception of agreement
Number Of Identified Performance Obligation At Inception Of Agreement
Number of identified performance obligation at inception of agreement.
Payment Cap Date on or after January 1, 2029 [Member]
Payment cap date on or after January one two thousand twenty nine [Member]
Payment cap date on or after January one two thousand twenty nine.
Award Date [Axis]
Contract with Customer, Liability [Abstract]
Contract with Customer, Liability [Abstract]
Sale of Stock
Sale of Stock [Domain]
Term loan amount
Amount received
Principal of senior secured term loan facilities
Proceeds from sales of available-for-sale securities
Proceeds From Sales Of Available For Sale Securities
Proceeds from sales of available for sale securities
Disposal Group, Including Discontinued Operation, Assets [Abstract]
Assets
Reversal of accrued co-promotion expenses
Reversal Of Accrued Co Promotion Expenses
Reversal of accrued co-promotion expenses.
Summary of Available for Sale Securities in Unrealized Loss Position, Fair Value and Gross Unrealized Loss By Length of Time Security in Continual Unrealized Loss Position
Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table Text Block]
Percentage of product manufacturing costs until manufacturing technology fully transferred
Percentage Of Product Manufacturing Costs Until Manufacturing Technology Fully Transferred
Percentage of product manufacturing costs until manufacturing technology fully transferred.
Transfers of assets from level 2 to 1
Fair Value Assets Level2 To Level1 Transfer Amount
Fair value assets level2 to level1 transfer amount.
Intangible assets
Deferred Tax Assets Intangible Assets
Deferred tax assets intangible assets.
Deferred tax asset for temporary difference
Deferred Tax Asset, Intra-Entity Transfer, Asset Other than Inventory
Inventories
Inventory, Policy [Policy Text Block]
Entity Central Index Key
Entity Central Index Key
Schedule of Available-for-sale Securities [Line Items]
Debt Securities, Available-for-Sale [Line Items]
Liquidity and Going Concern
Liquidity and Going Concern Policy [Policy Text Block]
Liquidity and going concern policy.
Warrants [Member]
Warrant [Member]
Forfeited, Shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Forfeitures in Period
Auditor Opinion [Text Block]
Changes in operating assets and liabilities:
Increase (Decrease) in Operating Capital [Abstract]
Discounted Cash Flow [Member]
Valuation Technique, Discounted Cash Flow [Member]
RIFA [Member]
Revenue Interest Financing Agreement [Member]
Revenue Interest Financing Agreement.
Revenue Interest Financing Agreement [Member]
Accounts receivable net current related parties.
Accounts Receivable Net Current Related Parties
Accounts receivable from related parties
Common stock, shares issued
Common Stock, Shares, Issued
Aggregate considerations received
Collaborative Arrangement Aggregate Consideration
Collaborative arrangement aggregate consideration.
Schedule Of Employee Service Share Based Compensation Allocation Of Recognized Period Costs [Table]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table]
Deduction
Contract With Customer Liability Deduction
Contract with customer liability deduction.
Risk-free interest rate, minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Minimum
Cash paid for transaction costs related to sale of future revenues
Transaction costs related to sale of future revenues
Cash paid for transaction costs related to sale of future revenues
Payments For Transaction Costs Related To Sale Of Future Revenues
Payments for transaction costs related to sale of future revenues.
Increase (Decrease) in Prepaid Expense and Other Assets
Prepaid expenses and other current assets
Disposal Group, Including Discontinued Operation, Operating Expense
Total operating costs and expenses
Total operating costs and expenses
Finance Lease, Liability, to be Paid, Year Five
2028
Award Date [Domain]
Loss from continuing operations
Income (Loss) from Continuing Operations, Net of Tax, Including Portion Attributable to Noncontrolling Interest
The Company
Business Description and Basis of Presentation [Text Block]
Repayments of finance lease liabilities
Financing cash flows from finance leases
Repayments Of Finance Lease Liabilities
Repayments of finance lease liabilities.
Expiration year two thousand twenty six.
Expiration Year Two Thousand Twenty Six [Member]
Expiration Year 2026 [Member]
Bank of Finland Interest Rate [Member]
Bank Of Finland Interest Rate [Member]
Bank of Finland interest rate.
Income Statement [Abstract]
TSR [Member]
Total Shareholder Return Awards [Member]
Total shareholder return awards.
Entity Address, State or Province
Entity Address, State or Province
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Assets [Abstract]
Assets
Derecognized [Member]
Derecognized.
Derecognized
Finance Lease, Liability, to be Paid, Year One
2024
Loss before provision for income taxes
Income (Loss) from Continuing Operations before Income Taxes, Noncontrolling Interest
Maximum sales milestones receivable.
Maximum Sales Milestones Receivable
Maximum sales milestones receivable
Revision of Prior Period [Axis]
Liability Related to Sale of Future Royalties
Liability Related To Sale Of Future Royalties [Text Block]
Liability related to sale of future royalties.
Other Than Temporary Impairment Loss Securities Available for Sale
Other than temporary impairment loss securities available for sale.
Other-than-temporary impairment loss
Repayment description
Repayment description.
Repayment Description
Accrued and Other Current Liabilities [Member]
Accrued And Other Current Liabilities [Member]
Accrued and other current liabilities.
Contract Liabilities [Member]
Contract Liabilities [Member]
Contract liabilities,
Operating lease liabilities, current
Increase Decrease In Operating Lease Liabilities Current
Increase (decrease) in operating lease liabilities, current.
Income (Loss) from Discontinued Operations and Disposal of Discontinued Operations, Net of Tax, Per Diluted Share
Income (Loss) from Discontinued Operations and Disposal of Discontinued Operations, Net of Tax, Per Diluted Share, Total
Income from discontinued operations per share - diluted
Deferred revenue non-current to related party
Due To Related Parties Deferred Revenue Noncurrent
Due to related parties deferred revenue noncurrent.
Concentration Risk Type
Concentration Risk Type [Domain]
Other Revenue - Contract Manufacturing [Member]
Development Revenue [Member]
Development and Other Revenue [Member]
Development and other revenue.
Product development obligations
Accrued Product Development Costs
Represents the long-term portion of the outstanding principal and accrued interest of advances in the form note agreements received by the entity to fund various product development efforts.
Recognized as Revenue
Contract with Customer, Liability, Revenue Recognized
Royalty revenue recognized as drug product revenue
Interest expense
Interest expense
Disposal Group, Including Discontinued Operation, Interest Expense
Customer Concentration Risk [Member]
Customer Concentration Risk [Member]
Other liabilities current due to related parties.
Other Liabilities Current Due to Related Parties
Accrued and other current liabilities to related party
Available for sale securities in continual unrealized loss position, estimated fair value
Available for sale securities in continual unrealized loss position, estimated fair value
Debt Securities, Available-for-Sale, Unrealized Loss Position
Unrecognized tax benefits description
Significant Change in Unrecognized Tax Benefits is Reasonably Possible, Estimated Range Not Possible
Accumulated amortization
Finance Lease Accumulated Amortization
Finance lease accumulated amortization.
Income (Loss) from Discontinued Operations, Net of Tax, Including Portion Attributable to Noncontrolling Interest
Income from discontinued operations, net of tax
Income from discontinued operations, net of tax
Finance lease cost:
Lease, Cost [Abstract]
Total intrinsic value of options exercised
Exercisable, Aggregate Intrinsic Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Intrinsic Value
Geographic Distribution
Geographic Distribution [Domain]
Beyond 2027
Finance Lease, Liability, to be Paid, after Year Five
Equity Method Investment, Nonconsolidated Investee
Equity Method Investment, Nonconsolidated Investee [Domain]
Raw materials
Inventory, Raw Materials, Gross
Series F [Member]
Series F Preferred Stock [Member]
Cover [Abstract]
Cover
Comprehensive Income (Loss)
Comprehensive Income, Policy [Policy Text Block]
Debt financing agreement.
Debt Financing Agreement [Member]
Net loss per share - basic
Net loss per share - basic
Earnings Per Share, Basic
Stock-based compensation expense
Effective Income Tax Rate Reconciliation Deduction Expense Share Based Compensation Cost
Effective income tax rate reconciliation deduction expense share based compensation cost.
Lessee, finance lease, option to extend
Lessee, Finance Lease, Option to Extend
Increase in valuation allowance
Valuation Allowance, Deferred Tax Asset, Increase (Decrease), Amount
Income Tax Contingency [Line Items]
Income Tax Contingency [Line Items]
Payment Cap Date in 2031 [Member]
Payment cap date in two thousand thirty one [Member]
Payment cap date in two thousand thirty one.
Gross Unrealized Holding Gains
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Gain, before Tax
Income Tax Contingency [Table]
Income Tax Contingency [Table]
Stock Issued During Period, Shares, Acquisitions
Consolidation of Fortis (Note 6)
Profit share liability
Deferred Revenue
Deferred revenue
Other Liabilities, Total
Other Liabilities
Due to related parties
Document Annual Report
Document Annual Report
Liability related to sale of future revenues, non-current
Liability Related To Sale Of Revenues NonCurrent
Liability related to sale of revenues noncurrent.
Summary of Common Stock Reserved for Future Issuance
Schedule Of Shares Of Common Stock Reserved For Future Issuance Table [Text Block]
Schedule of shares of common stock reserved for future issuance.
Investments, Debt and Equity Securities [Abstract]
License Revenue [Member]
License [Member]
License [Member]
Disposal Group Including Discontinued Operation Accounts Payable And Accrued Liabilities Noncurrent
Disposal group including discontinued operation accounts payable and accrued liabilities noncurrent.
Accrued and other current liabilities
Schedule of Cash and Cash Equivalents
Schedule of Cash and Cash Equivalents [Table Text Block]
Total stock-based compensation expense
Share-Based Payment Arrangement, Expense
Description of sales return
Description Of Sales Return
Description of sales return.
Finance leases
Finance Lease, Weighted Average Discount Rate, Percent
Long-Term Debt
Term loan
Senior secured term loan facilities, ending balance
Senior secured term loan facilities, ending balance
Recently Adopted Accounting Guidance [Policy Text Block]
Recently Adopted Accounting Guidance.
Recently Adopted Accounting Guidance
Highly liquid investment maturity period
Highly Liquid Investment Maturity Period
Highly liquid investment maturity period.
Retained Earnings (Accumulated Deficit), Total
Accumulated deficit
Retained Earnings (Accumulated Deficit)
Lessee, operating lease, expiration period
Lessee Operating Lease Expiration Period
Lessee, operating lease, expiration period.
Plan Name [Axis]
Plan Name
Two Thousand And Twenty Four Equity Incentive Plan [Member]
2024 Equity Incentive Plan.
2024 Equity Incentive Plan
Segment Reporting [Abstract]
Current portion classified to accrued and other current liabilities.
Current Portion Classified to Accrued and Other Current Liabilities
Less: Current Portion classified to accrued and other current liabilities
Stock options outstanding
Outstanding, Beginning Balance, Shares
Outstanding, Ending Balance, Shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Number
Current assets:
Assets, Current [Abstract]
Preferred stock redemption percentage
Preferred Stock, Redemption Terms
Number of common stock reserved for issuance
Shares reserved for future ESPP offering
Common Stock, Capital Shares Reserved for Future Issuance
Additional consideration based on net sales description
Additional Consideration Based On Net Sales
The amount of additional consideration based on net sales of product as defined under a collaboration agreement.
Schedule of Assumptions used to Estimate Fair Value of Stock Options Granted and Employee Stock Purchase Plans
Schedule Of Share Based Payment Award Stock Options And Employee Stock Purchase Plan Valuation Assumptions Table [Text Block]
Schedule of share based payment award stock options and employee stock purchase plan valuation assumptions.
United States [Member]
U.S. [Member]
UNITED STATES
Components of Income Tax Expense (Benefit), Continuing Operations [Abstract]
Investment Type [Axis]
Deferred Tax Liabilities, Net, Total
Net deferred tax liabilities
Deferred Tax Liabilities, Net
Schedule of Prepaid Expenses and Other Current Assets
Deferred Costs, Capitalized, Prepaid, and Other Assets Disclosure [Table Text Block]
Additional upfront payments
Collaborative arrangement additional upfront payments.
Collaborative Arrangement Additional Upfront Payments
Net Cash Provided by (Used in) Operating Activities
Net cash used in operating activities
Forfeited, Weighted Average Fair value at Grant
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeitures, Weighted Average Grant Date Fair Value
License and milestone revenue from a related party
License Fees And Milestones Revenue
Revenue from multiple-deliverable arrangements that include licensing fees and services revenue and the amount of consideration recognized during the period for milestones. Licensing revenue is consideration received from another party for the right to use, but not own, certain of the entity's intangible assets. Licensing arrangements include, but are not limited to, rights to use a patent, copyright, technology, manufacturing process, software or trademark. Licensing fees are generally, but not always, fixed as to amount and not dependent upon the revenue generated by the licensing party. An entity may receive licensing fees for licenses that also generate royalty payments to the entity. Services revenue may be derived by providing other, non-specified, services during the reporting period.
Product and Service
Product and Service [Domain]
Accumulated Other Comprehensive Income (Loss), Net of Tax, Total
Accumulated other comprehensive loss
Accumulated Other Comprehensive Income (Loss), Net of Tax
Lessee, operating lease, lease term
Lessee, Operating Lease, Term of Contract
Debt Instrument [Line Items]
Debt Instrument [Line Items]
Initial upfront payment
Initial Upfront Payment
Upfront payment.
Tax Period
Tax Period [Domain]
Deferred revenues from associated contracts
Deferred Revenues From Associated Contracts
Deferred revenues from associated contracts.
Selling, general and administrative
Disposal Group, Including Discontinued Operation, General and Administrative Expense
Property and equipment, net
Property and equipment, net
Property, Plant and Equipment, Net
Property and equipment
Lessee, Operating Lease, Liability, to be Paid, Year Four
2027
Investments
Investment, Policy [Policy Text Block]
Deferred revenue, net of current
Contract with Customer, Liability, Noncurrent
Deferred revenue, net of current
Operating activities
Net Cash Provided by (Used in) Operating Activities [Abstract]
Initial Term Loan [Member]
Initial Term Loan [Member]
Fair Value, Measurements, Recurring [Member]
Fair Value, Recurring [Member]
Miscellaneous receivables
Miscellaneous Receivables
Miscellaneous receivables.
Shareholders Equity And Stock Based Compensation [Abstract]
Shareholders equity and stock-based compensation.
Percentage of pre-launch inventory capitalized of aggregate inventory balance
Percentage Of Pre Launch Inventory Capitalized Of Aggregate Inventory Balance
Percentage of pre-launch inventory capitalized of aggregate inventory balance.
Vesting
Vesting [Axis]
Convertible Debt, Total
Convertible promissory note
Convertible Debt
Percentage increases on each anniversary of rent commencement date 2028
Percentage Increases On Anniversary Of Rent Commencement Date Option Two
Percentage increases on anniversary of rent commencement date option two.
Common stock, par value
Common Stock, Par or Stated Value Per Share
Short term investments maturity
Short Term Investments Maximum Maturity Period
Short term investments maximum maturity period.
Employee stock options [Member]
Cybersecurity Risk Management Positions or Committees Responsible [Text Block]
Non-key Account Hospital Listing Award [Member]
Non Key Account Hospital Listing Award [Member]
Non-key account hospital listing award.
Unrealized gain (loss) on investments, net of tax effect
OCI, Debt Securities, Available-for-Sale, Unrealized Holding Gain (Loss), before Adjustment, after Tax
Measurement Input Type
Measurement Input Type [Domain]
Contract with Customer, Liability, Total
Deferred revenues from associated contracts
Deferred Revenue
Deferred revenue
Contract with Customer, Liability
Balance at December 31, 2023
Balance at December 31, 2024
Disposal Groups, Including Discontinued Operations [Table]
Trade Accounts Receivable
Accounts Receivable [Policy Text Block]
Statement of Cash Flows [Abstract]
Counterparty Name [Axis]
Non-cash interest expense related to drug product revenue
Non-cash interest expense related to drug product revenue
Convertible promissory note
Convertible Debt Securities [Member]
Antidilutive Securities, Name
Antidilutive Securities, Name [Domain]
Equity method investment in unconsolidated variable interest entity
Beginning balance
Ending balance
Equity Method Investments
Equity method investments
Gross proceeds received from sale of revenue
Gross proceeds received from sale of revenue.
Other long-term liabilities
Increase (Decrease) in Other Noncurrent Liabilities
Selling, general and administrative [Member]
Selling, General and Administrative Expenses [Member]
Selling, General and Administrative Expenses [Member]
Entity
Entity [Domain]
Other
Deferred Tax Assets, Other
Equity Components
Equity Components [Axis]
Prepayment amount of 2024 to 2030
Prepayment amount
Prepayment amount.
Commercial milestone
Commercial Milestone
Commercial milestone.
Recorded Unconditional Purchase Obligation [Line Items]
Recorded Unconditional Purchase Obligation [Line Items]
Entity Address, Address Line One
Entity Address, Address Line One
Restricted time deposits
Restricted Time Deposits Noncurrent
Restricted time deposits noncurrent.
Employee-related Liabilities, Current, Total
Payroll and related accruals
Employee-related Liabilities, Current
Schedule Of Related Party Transactions By Related Party [Table]
Related Party Transaction [Table]
Granted, Shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period
Cybersecurity Risk Process for Informing Board Committee or Subcommittee Responsible for Oversight [Text Block]
Total shares of common stock reserved
Common Stock Shares Reserved
Common stock shares reserved.
Computer Equipment [Member]
Computer Equipment [Member]
Valuation Approach and Technique
Valuation Approach and Technique [Axis]
Property Plant And Equipment [Line Items]
Property, Plant and Equipment [Line Items]
Charged (Credited) to Statement of Operation
SEC Schedule, 12-09, Valuation Allowances and Reserves, Additions, Charge to Cost and Expense
Payment for Contingent Consideration Liability, Investing Activities
Contingent payment associated with business acquisition
2014 Equity Incentive Plan
Two Thousand And Fourteen Equity Incentive Plan [Member]
Two thousand and fourteen equity incentive plan.
Disposal percentage
Discontinued operations disposal percentage
Discontinued operations disposal percentage.
Subsequent Event Type [Axis]
Nonoperating Income (Expense), Total
Interest income and other income (expenses), net
Nonoperating Income (Expense)
Schedule of Weighted Impacts of Outstanding Anti-dilutive Securities Excluded from Calculation of Diluted Net Loss Per Share
Schedule of Antidilutive Securities Excluded from Computation of Earnings Per Share [Table Text Block]
Percentage of outstanding shares owned
Variable Interest Entity, Qualitative or Quantitative Information, Ownership Percentage
Risk-free interest rate
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate
U.S. government bonds [Member]
US Treasury and Government [Member]
Beijing Kangda Yongfu Pharmaceutical Co., LTD [Member]
Beijing Kangda Yongfu Pharmaceutical Co L T D [Member]
Beijing Kangda Yongfu Pharmaceutical Co., LTD.
Lessee, finance lease, existence of option to extend
Lessee, Finance Lease, Existence of Option to Extend [true false]
2026
Revenue Payment Cap Amount Due In Year Four
Revenue payment cap amount due in year four.
License revenue.
License Revenue [Member]
Variable consideration related to co-development billings
Variable Consideration Payment Received Related To Co Development Billings
Variable consideration payment received related to co-development billings.
RSUs outstanding
Unvested, Shares, Beginning Balance
Unvested, Shares, Ending Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Number
Entity Voluntary Filers
Entity Voluntary Filers
Amendment Flag
Amendment Flag
Total current
Current Income Tax Expense (Benefit)
Federal
Current Federal Tax Expense (Benefit)
Operating lease liabilities
Operating lease liabilities, non-current
Operating Lease, Liability, Noncurrent
Recorded Unconditional Purchase Obligation, to be Paid, Year One
Purchase obligations due 2025
Proceeds from sale of future revenues, gross
Gross Proceeds From Sale Of Future Revenues
Gross proceeds from sale of future revenues.
Federal [Member]
Domestic Tax Jurisdiction [Member]
Debt Instrument, Name [Domain]
Preferred stock, voting rights
Preferred Stock, Voting Rights
Operating Lease, Liability, Current, Statement of Financial Position [Extensible List]
Operating Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Contract With Customer Liability [Table]
Contract With Customer Liability [Table]
Contract With Customer Liability [Table]
Net loss
Net loss
Lessee Lease Description [Table]
Lessee, Lease, Description [Table]
U.S./RoW [Member]
U.S./RoW [Member]
United States And Rest Of World [Member]
United states and rest of world.
Loss on asset acquisition
Loss on asset acquisition
Loss on asset acquisition
Exercisable, Shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Number
Beijing Economic-Technological Development Area [Member]
Beijing Economic Technological Development Area [Member]
Beijing economic-technological development area.
Variable Rate
Variable Rate [Domain]
Research and development [Member]
Research and Development Expense [Member]
Series E [Member]
Series E Preferred Stock [Member]
Upfront, non-contingent, non-refundable and time-based payments
Proceeds From Upfront Non Contingent Non Refundable And Time Based Payments
Represents the total amount of non-contingent, non-refundable, upfront payments included under the collaborative agreement as arrangement consideration.
AstraZeneca U.S./RoW Agreement [Member]
AstraZeneca U.S./RoW Agreement [Member]
AstraZeneca U.S./RoW agreement member.
Gain (Loss) on Disposition of Property Plant Equipment, Excluding Oil and Gas Property and Timber Property
Loss on disposal of property and equipment
Equity Component
Equity Component [Domain]
Statistical Measurement
Statistical Measurement [Domain]
Balance Presented NetAgainst Contract Asset
Contract with customer liability net of balance presented against contract asset
Contract with customer liability net of balance presented against contract asset.
Document Financial Statement Error Correction [Flag]
Proceeds from Sale of Property, Plant, and Equipment, Total
Proceeds from sale of property and equipment
Proceeds from Sale of Property, Plant, and Equipment
Deferred:
Deferred Federal, State and Local, Tax Expense (Benefit) [Abstract]
Balance Sheet Components
Supplemental Balance Sheet Disclosures [Text Block]
Interest Expense, Debt, Total
Interest Expense, Debt
Interest expense
Percentage of excise tax on stock buyback
Percentage Of Excise Tax On Stock Buyback
Percentage of excise tax on stock buyback.
State
Deferred State and Local Income Tax Expense (Benefit)
Expiration period of stock options
Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Period
Net Transfer Price
Net Transfer Price [Member]
Net transfer price.
Net Transfer Price [Member]
Discounts And Rebates
Discounts And Rebates [Member]
Discounts and rebates.
Discounts and Rebates [Member]
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Text Block]
Furniture and Fixtures [Member]
Furniture and Fixtures [Member]
Redeemable Noncontrolling Interest, Equity, Carrying Amount, Total
Redeemable Noncontrolling Interest, Equity, Carrying Amount
Redeemable non-controlling interests
Common stock reserved for future issuance, Description
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Other Increases (Decreases) in Period, Description
Disaggregation Of Revenue [Table]
Disaggregation of Revenue [Table]
Cybersecurity Risk Management Processes Integrated [Flag]
Laboratory Equipment [Member]
Laboratory Equipment [Member]
Laboratory equipment.
Net loss
Net Income (Loss), Including Portion Attributable to Noncontrolling Interest
Net loss
Debt Instrument, Variable Interest Rate, Type [Extensible Enumeration]
Decrease (Increase) in Deferred Revenue
Increase Decrease In Deferred Revenue [Member]
Increase decrease in deferred revenue.
Decrease (Increase) in Deferred Revenue [Member]
Geographic Distribution
Geographic Distribution [Axis]
Preferred stock, shares issued
Preferred Stock, Shares Issued
Percentage of revenue interest on global net sales
Percentage Of Revenue Interest On Global Net Sales
Percentage of revenue interest on global net sales.
Contractual Sales Rebate [Member]
Contractual Sales Rebate [Member]
Contractual sales rebate.
Operating cash flows from operating leases
Cash payment related to lease
Operating Lease, Payments
Co-development, information sharing & committee services [Member]
Co Development Information Sharing And Committee Services [Member]
Co development information sharing and committee services.
Schedule of Maturities of Finance and Operating Leases Liabilities
Schedule Of Maturities Of Finance And Operating Leases Liabilities Table [Text Block]
Schedule of maturities of finance and operating leases liabilities.
Deferred tax liabilities fixed assets.
Fixed assets
Deferred Tax Liabilities Fixed Assets
Unconditional Purchase Obligations (Excluding Capital Stock Redemptions) [Abstract]
Commitments And Contingencies [Line Items]
Commitments And Contingencies [Line Items]
Commitments and contingencies.
Description of discontinued operations
Disposal Group, Including Discontinued Operation, Description and Timing of Disposal
Shares purchased by employees
Stock Issued During Period, Shares, Employee Stock Purchase Plans
Short-Term Investments, Total
Short-term investments
Short-Term Investments
Milestone Payments [Member]
Milestone payments [Member]
Milestone payments.
Interest expense recognized
Noncash Interest Expense Related To Sale Of Future Revenue
Noncash interest expense related to sale of future revenue.
Operating Lease, Expense
Operating lease
Prepaid expenses and other current assets
Total prepaid expenses and other current assets
Prepaid Expense and Other Assets, Current
Risk-free interest rate, maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Risk Free Interest Rate, Maximum
Forfeited, Weighted Average Exercise Price per Share
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Forfeitures in Period, Weighted Average Exercise Price
Disposal Group, Including Discontinued Operation, Prepaid and Other Assets, Current
Prepaid expenses and other current assets
Office Spaces
Office Spaces [Member]
Office spaces.
Net operating losses not benefitted
Effective Income Tax Rate Reconciliation Net Operating Losses Not Benefitted
Effective income tax rate reconciliation net operating losses not benefitted.
Collaborative Arrangement and Arrangement Other than Collaborative
Collaborative Arrangement and Arrangement Other than Collaborative [Axis]
Class of Stock
Class of Stock [Domain]
Agency bonds [Member]
Bonds [Member]
Other comprehensive gain (loss), net of taxes
Other Comprehensive Income (Loss), Net of Tax
Cumulative Effect, Period of Adoption, Adjustment [Member]
Cumulative Effect, Period of Adoption, Adjustment [Member]
Comprehensive loss
Comprehensive Income (Loss), Net of Tax, Attributable to Parent
Common Stock, Shares, Outstanding, Ending Balance
Common Stock, Shares, Outstanding, Beginning Balance
Common stock outstanding
Common stock, shares outstanding
Common Stock, Shares, Outstanding
Finite-Lived Intangible Assets, Major Class Name
Finite-Lived Intangible Assets, Major Class Name [Domain]
Fair Value Measurements
Fair Value Measurement, Policy [Policy Text Block]
Schedule of Components of Provision For Income Taxes
Schedule of Components of Income Tax Expense (Benefit) [Table Text Block]
Purchases of available-for-sale securities
Payments to Acquire Debt Securities, Available-for-Sale
Preferred stock, par value
Preferred Stock, Par or Stated Value Per Share
Percentage of Revenue [Member]
Revenue Benchmark [Member]
Interest income and other income (expenses), net
Interest income and other income (expenses), net
Disposal Group Including Discontinued Operation Interest Income And Other Expenses Net
Disposal group including discontinued operation interest income and other expenses net.
Antidilutive Securities
Antidilutive Securities [Axis]
Corporate bonds [Member]
Corporate Bond Securities [Member]
Cybersecurity Risk Process for Informing Management or Committees Responsible [Text Block]
2014 ESPP [Member]
Two Thousand And Fourteen Employee Stock Purchase Plan [Member]
Two thousand and fourteen employee stock purchase plan.
NovaQuest [Member]
NovaQuest Capital Management [Member]
NovaQuest Capital Management.
NovaQuest Capital Management [Member]
Cash
Cash
Foreign
Deferred Foreign Income Tax Expense (Benefit)
Discontinued Operations and Disposal Groups [Abstract]
Product Development Obligations
Product Development Obligations Disclosure [Text Block]
Product development obligation disclosure.
Entity Interactive Data Current
Entity Interactive Data Current
Cash Acquired from Acquisition
Cash acquired from consolidation of Fortis
Product [Member]
Product Revenue, Net [Member]
Product [Member]
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Liabilities [Abstract]
Liabilities
Deferred revenue current to related party
Due To Related Parties Deferred Revenue Current
Due to related parties deferred revenue current.
Drug product revenue from a related party
Drug Product Revenue From Related Party
Drug product revenue from related party.
Deferred Approval Milestone [Member]
Deferred Approval Milestone [Member]
Deferred approval milestone.
Accounting Standards Update
Accounting Standards Update [Domain]
AstraZenecaAB [Member]
Astra Zeneca A B [Member]
AstraZeneca AB.
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Total
Reserves and accruals
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals
Vested, Weighted Average Fair value at Grant
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period, Weighted Average Grant Date Fair Value
Related Party Transactions
Related Party Transactions Disclosure [Text Block]
Balance Sheet Location
Statement of Financial Position Location, Balance [Axis]
Less: Interest
Finance Lease, Liability, Undiscounted Excess Amount
Statistical Measurement
Statistical Measurement [Axis]
Series D [Member]
Series D Preferred Stock [Member]
Amortization of right-of-use assets
Finance Lease, Right-of-Use Asset, Amortization Continuing Operations
Finance lease, right-of-use asset, amortization continuing operations.
Maximum payment cap amount
Maximum payment cap amount.
Operating lease cost
Operating Lease, Cost
Operating leases
Due to related parties, noncurrent
Other liabilities noncurrent due to related parties.
Other Liabilities Noncurrent Due to Related Parties
Assets, Fair Value Disclosure, Total
Total fair value of financial assets
Assets, Fair Value Disclosure
Related Party
Related and Nonrelated Parties [Domain]
Total lease cost
Lease, Cost
Discontinued Operation, Tax Effect of Discontinued Operation
Provision for income taxes
Income from discontinued operations, net of tax
Total lease assets
Finance Lease And Operating Lease Assets
Finance lease and operating lease assets.
Astellas and AstraZeneca [Member]
Astellas And Astra Zeneca [Member]
Astellas and AstraZeneca.
Operating cash flows from finance leases
Finance Lease, Interest Payment on Liability
Collaboration Arrangements and Revenues
Collaborative Arrangement And Revenues Policy [Text Block]
Collaborative arrangement and revenues.
Astellas Agreement [Member]
Astellas agreement.
Astellas Agreement [Member]
Commercial paper [Member]
Commercial Paper [Member]
Accrued Interest
Interest Payable
Shares reserved for future stock options and RSUs grant
Share-Based Compensation Arrangement by Share-Based Payment Award, Number of Shares Available for Grant
Currency Translation
Equity Method Investment Increase Decrease From Currency Translation
Equity method investment increase (decrease) from currency translation.
Percentage of ownership changes
Experience Historical Ownership Changes
Experience historical ownership changes.
Granted, Weighted Average Fair value at Grant
Weighted-average fair value of awards granted
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Grants in Period, Weighted Average Grant Date Fair Value
Non-vested stock option awards granted that will be recognized on a straight-line basis over the weighted-average period
Share-Based Payment Arrangement, Nonvested Award, Cost Not yet Recognized, Period for Recognition
Commitments And Contingencies [Table]
Commitments And Contingencies [Table]
Commitments and contingencies.
Foreign net operating loss [Member]
Foreign Tax Jurisdiction [Member]
Operating lease right-of-use assets
Increase Decrease In Operating Lease Right Of Use Assets
Increase (decrease) in operating lease right-of-use assets.
Provision for co-development services
Provision For Co Development Services
Provision for co-development services.
Machinery [Member]
Machinery and Equipment [Member]
Amount constrained related to drug product shipment
Contract with Customer, Liability, Cumulative Catch-up Adjustment to Revenue, Change in Estimate of Transaction Price
Total
Recorded Unconditional Purchase Obligation
Schedule of Long Lived Assets by Geographic Area
Long-Lived Assets by Geographic Areas [Table Text Block]
U.S./RoW and China [Member]
United States And Rest Of World And China [Member]
United states and rest of world and china.
Total net deferred tax assets
Deferred Tax Assets, Net
Increase Decrease In Accrued Interest Expense Related To Sale Of Future Revenues
Increase (decrease) in accrued interest expense related to sale of future revenues
Accrued interest expense related to sale of future revenues
Research and Development Expenses
Research and Development Expense, Policy [Policy Text Block]
Ownership [Domain]
Income Statement Location
Statement of Income Location, Balance [Axis]
Total assets
Assets
Expected term (in years)
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Term
Commercial sales milestone
Commercial Sales Milestone
Represents the amount of milestone payments related to commercial sales under the collaborative agreement.
Impact of change in accounting principle upon adoption of ASU 2018-02 [Member]
Impact Of Change In Accounting Principle Upon Adoption Of A S U201802 [Member]
Impact of change in accounting principle upon adoption of ASU 2018-02.
Received from sale of revenue
Received From Sale of Revenue
Received from sale of revenue.
Tax Period
Tax Period [Axis]
Liability Related To Sale Of Revenue Current
Liability related to sale of revenue current.
Less: Current portion classified to accrued and other current liabilities
Less: Current portion classified to accrued and other current liabilities
Debt Instrument [Table]
Schedule of Long-Term Debt Instruments [Table]
Impairment of long-lived assets
Impairment of Long-Lived Assets to be Disposed of
Foreign
Current Foreign Tax Expense (Benefit)
Foreign
Income (Loss) from Continuing Operations before Income Taxes, Foreign
Vested, Shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Vested in Period
Restricted Cash and Cash Equivalents, Noncurrent, Total
Restricted time deposits
Restricted Cash and Cash Equivalents, Noncurrent
Business Acquisition [Line Items]
Entity Address, City or Town
Entity Address, City or Town
Accumulated Other Comprehensive Loss [Member]
AOCI Attributable to Parent [Member]
Equity [Abstract]
Investment income (loss)
Income (Loss) from Equity Method Investments
Share of Net Income
Total Consideration
Cash Consideration Received Under Collaboration Agreement
The total cash consideration received under a collaboration agreement that has been allocated to the different significant units of accounting and includes the portion that has been deferred for revenue recognition.
Cash Consideration Received Under Collaboration Agreement
Total Consideration
Other
Effective Income Tax Rate Reconciliation, Other Adjustments, Percent
Auditor Location
Auditor Location
Effective Income Tax Rate Reconciliation, Percent [Abstract]
Cybersecurity Risk Materially Affected or Reasonably Likely to Materially Affect Registrant [Flag]
Forfeited, Shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Forfeited in Period
Finance Lease, Liability, to be Paid, Year Two
2025
Debt Securities, Available-for-Sale, Unrealized Loss Position, Fair Value [Table]
Cash payments for restructuring
Payments for Restructuring
Constrained for Future Recognition [Member]
Deferred For Future Recognition [Member]
Deferred for future recognition.
Balance at Beginning of Year
Balance at End of Year
SEC Schedule, 12-09, Valuation Allowances and Reserves, Amount
Equity and Stock-based Compensation
Shareholders' Equity and Share-Based Payments [Text Block]
2023
Revenue Payment Cap Amount Due Next Twelve Months
Revenue payment cap amount due next twelve months.
Disposal group including discontinued operation interest and other net.
Disposal Group Including Discontinued Operation Interest And Other Net [Abstract]
Interest and other, net
Net Cash Provided by (Used in) Continuing Operations
Net Cash Provided by (Used in) Continuing Operations, Total
Cash and cash equivalents of continuing operations
Payment to options exercised
Payment to Options Exercised
Payment to options exercised
Unconditional Purchase Obligation, Category of Goods or Services Acquired [Domain]
HiFiBiO Agreement [Member]
Hi Fi Bi O Agreements [Member]
HiFiBiO Agreement.
Debt Securities, Available-for-Sale, Unrealized Loss Position [Line Items]
Redeemable Preferred Stock Member
Redeemable Preferred Stock [Member]
Depreciation, Total
Depreciation
Depreciation
Depreciation expense for the continuing operations
Revision of Prior Period [Domain]
Schedule Of Segment Reporting Information By Segment [Table]
Schedule of Segment Reporting Information, by Segment [Table]
Disposal Group, Including Discontinued Operation, Assets, Current
Total current assets held for sale
Current assets held for sale
Asset acquisition policy.
Asset Acquisition Policy [Policy Text Block]
Asset Acquisition
Europe [Member]
Europe [Member]
Cybersecurity Risk Third Party Oversight and Identification Processes [Flag]
Credit Losses – Available-For-Sale Debt Securities
Credit Loss, Financial Instrument [Policy Text Block]
Cybersecurity Risk Management Positions or Committees Responsible Report to Board [Flag]
Construction in progress [Member]
Construction in Progress [Member]
Regulatory Milestone [Member]
Regulatory Milestones [Member]
Regulatory milestone.
Contract with Customer, Liability, Change in Timeframe, Performance Obligation Satisfied, Revenue Recognized
Changes in revenue from changes to estimated variable consideration
Series A [Member]
Series A Preferred Stock [Member]
Series A Preferred Shares [Member]
Acquisition And Variable Interest Entity [Abstract]
Acquisition and variable interest entity abstract.
2005 Stock Plan
Two Thousand And Five Stock Plan [Member]
Two thousand and five stock plan.
State
Current State and Local Tax Expense (Benefit)
Prepaid Expense and Other Assets, Current [Abstract]
China performance obligation [Member]
China Performance Obligation [Member]
China performance obligation.
Expired, Shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Expirations in Period
Valuation And Qualifying Accounts Disclosure [Line Items]
SEC Schedule, 12-09, Valuation and Qualifying Accounts Disclosure [Line Items]
Operating leases
Operating Lease, Weighted Average Discount Rate, Percent
Capitalized research and development expenses
Deferred Tax AssetsTax Capitalized Research And Development Expenses
Deferred tax assets tax capitalized research and development expenses.
Income Taxes [Table]
Income Taxes [Table]
Income taxes.
Segment Reporting, CODM, Individual Title and Position or Group Name [Extensible Enumeration]
Fair Value Disclosures [Abstract]
Finance Leases
Finance Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract]
Entity Public Float
Entity Public Float
Other tax credit carryforwards
Deferred Tax Assets, Tax Credit Carryforwards, Other
Schedule Of Leases [Table]
Schedule Of Leases [Table]
Schedule of leases.
Astellas Europe Agreement [Member]
Astellas Europe Agreement [Member]
Astellas Europe Agreement.
Issuance of common stock under ATM Program
Stock Issued During Period, Value, New Issues
Net deferred tax assets
Deferred Tax Assets, Net of Valuation Allowance
Interest expense recognized
Non-cash interest expense related to sale of future revenues
Non Cash Interest Expense Related To Sale Of Future Revenues
Non cash interest expense related to sale of future revenues.
Lessee Lease Description [Line Items]
Lessee, Lease, Description [Line Items]
Current liabilities:
Liabilities, Current [Abstract]
Cornea Products [Member]
Cornea Products [Member]
Cornea products.
Lease Contractual Term
Lease Contractual Term [Axis]
Foreign exchange rate differential
Unrecognized Tax Benefits, Increase (Decrease) Resulting from Foreign Currency Translation
Unrecognized tax benefits, increase (decrease) resulting from foreign currency translation.
Percentage of Accounts Receivable [Member]
Accounts Receivable [Member]
Accounts Receivable [Member]
Accrued liabilities
Accrued Liabilities
Accrued Liabilities, Total
Product development obligations
Product Development Costs
Product Development Costs
Accounts receivable from related parties
Increase (Decrease) in Accounts Receivable, Related Parties
Corporate alternative minimum tax percentage
Corporate Alternative Minimum Tax Percentage
Corporate alternative minimum tax percentage.
Document Type
Document Type
Accounting Standards Update
Accounting Standards Update [Axis]
Contract with customer liability increase decrease in revenue due to changes to estimated variable consideration
Contract With Customer Liability Increase Decrease In Revenue Due To Changes To Estimated Variable Consideration
Contract with customer liability increase decrease in revenue due to changes to estimated variable consideration.
Cost, Product and Service [Extensible List]
Cost, Product and Service [Extensible Enumeration]
Title of 12(b) Security
Title of 12(b) Security
Total cash and cash equivalents
Cash and cash equivalents
Cash and Cash Equivalents, at Carrying Value
Purchase of common stock shares at discount
Share-Based Compensation Arrangement by Share-Based Payment Award, Discount from Market Price, Purchase Date
Valuation Allowances for Rebates, Discounts and Adjustments [Member]
Valuation Allowances for Rebates, Discounts and Adjustments [Member]
Percentage increases on each anniversary of rent commencement date 2023
Percentage Increases On Each Anniversary Of Rent Commencement Date
Percentage increases on each anniversary of rent commencement date.
Balance Sheet Location
Statement of Financial Position Location, Balance [Domain]
Lessee, Operating Lease, Liability, to be Paid, Year Five
2028
Components of Lease Expense
Lease, Cost [Table Text Block]
Product Revenue, Net
Product Revenue Policy Policy [Text Block]
Product revenue policy.
Cybersecurity Risk Management, Strategy, and Governance [Line Items]
Statement of Stockholders' Equity [Abstract]
Document Fiscal Period Focus
Document Fiscal Period Focus
Research and Development Expense, Total
Research and development
Research and Development Expense
Cash paid for payroll taxes on restricted stock unit releases
Payment, Tax Withholding, Share-Based Payment Arrangement
Drug Product Revenue Policy [Text Block]
Drug product revenue.
Drug Product Revenue, Net
California [Member]
CALIFORNIA
Granted, Shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Gross
Less: Transaction costs
Transaction Costs Related To Sale Of Future Revenues
Transaction costs related to sale of future revenues.
Interest Paid Related to Sale of Future Revenues
Interest paid related to sale of future revenues.
Interest paid
Development and regulatory approval milestones
Development And Regulatory Approval Milestones
Represents the potential amount of milestone payments related to development and regulatory approval under the collaborative agreement.
Percentage of common stock reserved for future issuance
Percentage of common stock reserved for future issuance
Share-Based Compensation Arrangement by Share-Based Payment Award, Percentage of Outstanding Stock Maximum
Profit Share
Profit Share [Member]
Profit share.
Profit Share [Member]
Earliest Tax Year [Member]
Earliest Tax Year [Member]
Foreign subsidiaries [Member]
Geographic Distribution, Foreign [Member]
Cash dividend percentage
Preferred Stock, Dividend Rate, Percentage
Disaggregation of Revenue [Abstract]
Non-cash change in accrued interest expense and payments related to sale of future revenues
Non-cash change in accrued interest expense and payments related to sale of future revenues.
Non-cash interest expense related to sale of future revenues
Property, Plant and Equipment, Gross, Ending Balance
Property, Plant and Equipment, Gross, Beginning Balance
Property, Plant and Equipment, Gross, Total
Property and equipment, gross
Property, Plant and Equipment, Gross
Liability Related to Sale of Future Revenues
Liability Related To Sale of Future Revenue [Text Block]
Liability related to sale of future revenue.
Summary of Outstanding Non-cancelable Purchase Obligations
Recorded Unconditional Purchase Obligations [Table Text Block]
Product Information [Line Items]
Variable Interest Entity Disclosure [Text Block]
Consolidated Variable Interest Entity - Fortis
Subsequent Event Type [Domain]
Other Discounts and Rebates [Member]
Other Discounts And Rebates [Member]
Other discounts and rebates.
Finance lease right-of-use assets
Total finance lease right-of-use assets
Finance lease right-of-use assets, net
Finance lease right-of-use assets
Finance Lease, Right-of-Use Asset, after Accumulated Amortization
Leases
Lessee, Leases [Policy Text Block]
Repayments of Related Party Debt
Payment to related parties
Other revenue patent transfer .
Other Revenue Patent Transfer [Member]
Other Revenue - Patent Transfer [Member]
Disposal Group Including Discontinued Operation Equity Method Investment In Unconsolidated Variable Interest Entity
Disposal Group Including Discontinued Operation Equity Method Investment In Unconsolidated Variable Interest Entity.
Equity method investment in unconsolidated variable interest entity
Disposal Groups, Including Discontinued Operations, Disclosure [Text Block]
Discontinued Operations
SEC Schedule, 12-09, Valuation Allowances and Reserves Type
SEC Schedule, 12-09, Valuation Allowances and Reserves Type [Axis]
Summary of Finance and Operating Lease Right of Use Assets by Geographical Location
Summary Of Finance And Operating Lease Right Of Use Assets By Geographical Location Table [Text Block]
Summary of Finance and Operating Lease Right of Use Assets by Geographical Location.
Redeemable non-controlling interests.
Redeemable non-controlling interests
Redeemable non-controlling interests
Stock Option Awards [Member]
Stock Option Awards [Member]
Stock option awards.
Accrued restructuring charges.
Accrued Restructuring Charges
Accrued restructuring charges
Available for sale securities in continual unrealized loss position, 12 months or more, estimated fair value
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer
Shares issued from stock plans, net of payroll taxes paid, Shares
Shares Issued From Stock Plans Net Of Payroll Taxes Paid Shares
Shares issued from stock plans net of payroll taxes paid shares.
Financial Instruments
Financial Instruments [Domain]
Disposal Group, Including Discontinued Operation, Assets, Noncurrent
Total long-term assets held for sale
Long-term assets held for sale
Potential milestone payments
Potential Milestones
Represents the total potential amount of milestone payments related to development, regulatory approval and commercial sales under the collaborative agreement.
Sale of Stock
Sale of Stock [Axis]
Investing activities
Net Cash Provided by (Used in) Investing Activities [Abstract]
Investments [Domain]
Eluminex [Member]
Eluminex Collaboration Agreement [Member]
Eluminex collaboration agreement.
Category of Item Purchased
Category of Item Purchased [Axis]
Money market funds
Money Market Funds, at Carrying Value
Shorenstein Properties LLC [Member]
Shorenstein Properties L L C [Member]
Shorenstein properties LLC.
Disposal Group Including Discontinued Operation Revenue [Abstract]
Disposal group including discontinued operation revenue.
Revenue:
Other Risks and Uncertainties
Other Risks And Uncertainties Policy [Text Block]
Other Risks and Uncertainties.
Drug product revenue recognized
Total revenue
Drug product revenue recognized
Statement of Comprehensive Income [Abstract]
Disposal Groups, Including Discontinued Operations [Table Text Block]
Schedule of Financial Results, Carrying Value of Assets and Liabilities and Significant Non-Cash Items and Capital Expenditures of Discontinued Operations
Income Taxes
Income Tax Disclosure [Text Block]
Decrease due to prior positions
Unrecognized Tax Benefits, Decrease Resulting from Prior Period Tax Positions
Schedule of Reconciliation Between Statutory Federal Income Tax Rate and Effective Tax Rate
Schedule of Effective Income Tax Rate Reconciliation [Table Text Block]
Disposal Group, Including Discontinued Operation, Interest Income
Cybersecurity Risk Management, Strategy, and Governance [Abstract]
Ownership [Axis]
Accrued and other current liabilities
Business combination, recognized identifiable assets acquired and liabilities assumed business combination, accrued and other current liabilities
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed Business Combination, Accrued and other current liabilities
Business acquistion payment to support continued development obligations
Payment made for acquired in-process research and development asset
Payments to Acquire in Process Research and Development
Upfront, non-contingent and time-based payments received
Proceeds From Upfront Non Contingent And Time Based Payments
Represents the amount of fixed and determinable non-contingent upfront payments included under the collaborative agreement as arrangement consideration.
Selling, General and Administrative Expense, Total
Selling, general and administrative
Selling, General and Administrative Expense
Series B [Member]
Series B Preferred Stock [Member]
Fair value of the acquired in process research and development assets.
Fair value of the acquired in process research and development assets
Fair value of the acquired IPR&D assets
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Period Increase (Decrease), Total
Increase in number of shares of common stock reserved for future issuance, shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Period Increase (Decrease)
Debt Securities, Available-for-Sale [Table]
Convertible promissory note [Member]
Convertible promissory note.
Convertible promissory note [Member]
Other
Other Accrued Liabilities, Current
Increase (Decrease) in Accounts Payable, Total
Increase (Decrease) in Accounts Payable
Accounts payable
Entity Address, Address Line Two
Liabilities and Equity [Abstract]
Liabilities, redeemable non-controlling interests and deficit
Schedule of Revenue by Major Customers by Reporting Segments [Table Text Block]
Schedule of Customer Concentration by Collaboration Partners
Maximum future milestone payments
Maximum Future Milestone Payments
Maximum future milestone payments.
PRSUs [Member]
Performance Based Restricted Stock Awards [Member]
Performance based restricted stock awards.
Document Period End Date
Document Period End Date
Net Cash Provided by (Used in) Financing Activities
Net cash (used in) provided by financing activities
FibroGen Europe [Member]
Fibrogen Europe Oy [Member]
Fibro Gen Europe Oy.
ICFR Auditor Attestation Flag
ICFR Auditor Attestation Flag
Discount rate applied
Alternative Investment, Measurement Input
Total
Effective Income Tax Rate Reconciliation, Percent
Summary of RSU,PRSU and TSR Awards
Schedule Of ShareBased Compensation Restricted Stock Units Perfomance Based Restricted Stock And Total Shareholders Return Award Activity [TableTextBlock]
Schedule of shareBased compensation restricted stock units perfomance based restricted stock and total shareholders return award activity.
Future revenue granted
Future revenue granted.
Collaboration services and other revenue from a related party
Collaboration Services And Other Revenue
Revenue recognized from co-development services, manufacturing of clinical supplies, committee services and information services and other revenue.
Anti-dilutive securities excluded from computation of net loss per share
Antidilutive Securities Excluded from Computation of Earnings Per Share, Amount
Payment Cap Date on or before December 31, 2028 [Member]
Payment cap date on or before December thirty one two thousand twenty eight [Member]
Payment cap date on or before December thirty one two thousand twenty eight.
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition, Total
Stock-based compensation
APIC, Share-Based Payment Arrangement, Increase for Cost Recognition
Ownership Percentage
Equity Method Investment, Ownership Percentage
Collaborative Arrangement And Revenues Disclosure [Text Block]
Collaborative arrangement and revenues.
Collaboration Agreements, License Agreement and Revenues
Disposal Group Including Discontinued Operation Operating Lease Liability Noncurrent
Disposal group including discontinued operation operating lease liability noncurrent.
Operating lease liabilities, non-current
AstraZeneca [Member]
AstraZeneca Agreements [Member]
Astra Zeneca Agreements [Member]
Astra Zeneca agreements.
Total accrued and other current liabilities
Accrued Liabilities, Current
Beyond 2027
Lessee, Operating Lease, Liability, to be Paid, after Year Five
Segment Reporting, CODM, Profit (Loss) Measure, How Used, Description
Income Tax Expense (Benefit)
Benefit from income taxes
Benefit from income taxes
Rent increase commencement year second option
Scheduled Rent Commencement Year Option Two
Scheduled rent commencement year option two.
Operating loss carryforwards expiration year
Operating Loss Carryforwards Expiration Year
Operating loss carryforwards expiration year.
Trading Symbol
Trading Symbol
Business Combinations [Abstract]
Variable Rate
Variable Rate [Axis]
Stockholders' Equity Attributable to Parent, Ending Balance
Stockholders' Equity Attributable to Parent, Beginning Balance
Equity, Attributable to Parent
Total stockholders' deficit attributable to FibroGen
SEC Schedule, 12-09, Valuation and Qualifying Accounts [Abstract]
Accrued restructuring charge current.
Accrued Restructuring Charge Current
Accrued restructuring charge
Schedule of Investments [Abstract]
Milestone payments.
Milestone Payments
FibroGen International [Member]
FibroGen international.
Preclinical and clinical trial accruals
Accrued Preclinical And Clinical Trial Current
Total of the carrying values as of the balance sheet date of obligations incurred through that date and payable for obligations related to pre-clinical and clinical trial activities, including those performed by third parties. Used to reflect the current portion of the liabilities (due within one year or within the normal operating cycle if longer).
Subtotal
Deferred Tax Assets, Gross
Loss Contingency Accrual, Beginning Balance
Loss Contingency Accrual, Ending Balance
Loss Contingency Accrual
Litigation settlement amount
Senior secured term loan facilities.
Senior Secured Term Loan Facilities [Member]
Impairment of inatangible assets finite lived
Impairment of Intangible Assets, Finite-Lived
Long-Lived Tangible Asset
Long-Lived Tangible Asset [Axis]
Warrants to purchase common stock outstanding
Class of Warrant or Right, Outstanding
U.S. government bonds
US Government Securities, at Carrying Value
Total other long-term liabilities
Other Liabilities, Noncurrent
Other long-term liabilities
Other long-term liabilities
Stock-Based Compensation
Share-Based Payment Arrangement [Policy Text Block]
Effective annual interest rate related to sale of future revenues
Effective Annual Interest Rate Related To Sale Of Future Revenues
Effective Annual Interest Rate Related To Sale Of Future Revenues
RSUs [Member]
Restricted Stock Unit [Member]
Restricted Stock Units (RSUs) [Member]
Related Party Transactions [Abstract]
Income from discontinued operations per share - basic
Income (Loss) from Discontinued Operations and Disposal of Discontinued Operations, Net of Tax, Per Basic Share
Income (Loss) from Discontinued Operations and Disposal of Discontinued Operations, Net of Tax, Per Basic Share, Total
Deferred revenue from related parties
Increase (Decrease) in Deferred Revenue
Commercial paper
Commercial Paper, at Carrying Value
Schedule Of Property Plant And Equipment [Table]
Property, Plant and Equipment [Table]
Cybersecurity Risk Management, Strategy, and Governance [Table]
Lease Amendment [Member]
Lease Amendment [Member]
Lease amendment.
Unrealized loss on equity investments
Unrealized Loss Gain On Equity Investments
Unrealized loss (gain) on equity investments.
Upfront payment
Collaborative Arrangement Aggregate Consideration For Milestone And Upfront Payments
Collaborative arrangement aggregate consideration for milestone and upfront payments.
Aggregate consideration received for milestone and upfront payments
Selling, General and Administrative Expenses
Selling, General and Administrative Expenses, Policy [Policy Text Block]
Contract with Customer Liability [Line Items]
Contract With Customer Liability [Line Items]
Contract with customer liability.
ATM Program [Member]
ATM Program.
Cybersecurity Risk Management Expertise of Management Responsible [Text Block]
Schedule of Recorded Stock-Based Compensation Expense
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Table Text Block]
Accrued Liabilities
Accrued Liabilities [Member]
Measurement Input Discount Rate [Member]
Measurement Input, Discount Rate [Member]
Termination date of equity incentive plan
Share-Based Compensation Arrangement by Share-Based Payment Award, Expiration Date
Measurement Input Type
Measurement Input Type [Axis]
Total deferred
Deferred Income Tax Expense (Benefit)
Geographical
Geographical [Axis]
Finance Lease, Liability, to be Paid, Year Three
2026
Discounts And Rebates Current
Discounts And Rebates Current [Member]
Discounts and rebates current.
Gross Unrealized Holding Losses
Debt Securities, Available-for-Sale, Accumulated Gross Unrealized Loss, before Tax
Unrecognized compensation costs
Share-Based Payment Arrangement, Nonvested Award, Option, Cost Not yet Recognized, Amount
Leases [Abstract]
Use of Estimates
Use of Estimates, Policy [Policy Text Block]
Payment Cap Date after January 1, 2030 [Member]
Payment cap date after January one two thousand thirty [Member]
Payment cap date after January one two thousand thirty.
Burdened manufacturing costs
Manufacturing Costs
Summary of Amounts Recognized as Revenue
Deferred Revenue, by Arrangement, Disclosure [Table Text Block]
Optional rights to extend lease
Number Of Optional Rights To Extend Lease
Number of optional rights to extend lease.
Collaborative Arrangement [Member]
Collaborative Arrangement [Member]
Lessee, finance lease, expiration period
Lessee Finance Lease Expiration Period
Lessee, finance lease, expiration period.
Concentration risk, percentage
Concentration Risk, Percentage
Series G [Member]
Series G Preferred Stock [Member]
Cash and Cash Equivalents, Policy [Policy Text Block]
Cash, Cash Equivalents
Fortis Therapeutics [Member]
Fortis Therapeutics.
Fortis Therapeutics [Member]
Schedule of Lease Term and Discount Rate
Schedule Of Lease Term And Discount Rate Table [Text Block]
Schedule of lease term and discount rate.
Operating Lease, Liability, Noncurrent, Statement of Financial Position [Extensible List]
Operating Lease, Liability, Noncurrent, Statement of Financial Position [Extensible Enumeration]
Class Of Stock [Line Items]
Class of Stock [Line Items]
Schedule of Business Acquisitions, by Acquisition [Table]
Schedule of Allocation of Purchase Consideration Based on Estimated Fair Values of Acquired Assets
Expected volatility, minimum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Minimum
Agency bonds [Member]
Agency Bonds [Member]
Agency bonds.
Operating lease liabilities, non-current
Increase Decrease In Operating Lease Liabilities Non Current
Increase (decrease) in operating lease liabilities, non-current.
Sale proceeds from common stock
Sale Of Common Stock Aggregate Offering Price Authorized
Sale of common stock aggregate offering price authorized.
Disposal Group, Including Discontinued Operation, Inventory, Current
Inventories
Expected dividend yield
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Dividend Rate
Roll-forward of Related Contract Liabilities
Contract with Customer, Contract Asset, Contract Liability, and Receivable [Table Text Block]
Finance Lease, Liability, Current, Statement of Financial Position [Extensible Enumeration]
Accounting Policy [Line Items]
Accounting Policy [Line Items]
Accounting policy.
Security Exchange Name
Security Exchange Name
Summary of Amortized Cost, Gross Unrealized Holding Gains or Losses, and Fair Value of Investments
Schedule of Available-for-Sale Securities Reconciliation [Table Text Block]
Proceeds from Sale, Maturity and Collection of Investments, Total
Proceeds from maturities of investments
Proceeds from Sale, Maturity and Collection of Investments
Income (Loss) from Continuing Operations, Per Basic Share
Loss from continuing operations per share - basic
Before December 31, 2028 [Member]
Payment Period One [Member]
Payment Period One [Member]
Payment Period One [Member]
Counterparty Name [Domain]
Deferred Tax Assets, Tax Credit Carryforwards, Total
Tax credit carryforwards
Deferred Tax Assets, Tax Credit Carryforwards
Business Acquisition, Acquiree
Business Acquisition, Acquiree [Domain]
Acquisition And Variable Interest Entity [Table]
Acquisition And Variable Interest Entity [Table]
Acquisition and variable interest entity table.
Schedule of Revenue by Geographic Area
Revenue from External Customers by Geographic Areas [Table Text Block]
Litigation settlement
Litigation settlement current.
Litigation Settlement Current
Gross Accounts Receivable [Member]
Gross Accounts Receivable [Member]
Gross accounts receivable.
Cumulative Effect, Period of Adoption
Cumulative Effect, Period of Adoption [Axis]
Long-Lived Tangible Asset
Long-Lived Tangible Asset [Domain]
Class of Stock
Class of Stock [Axis]
Senior secured term loan facilities, non-current
Secured Long-Term Debt, Noncurrent
Accrued interest, unrecognized tax benefits
Unrecognized Tax Benefits, Interest on Income Taxes Accrued
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Ending Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Beginning Balance
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment, Total
Less: accumulated depreciation
Accumulated Depreciation, Depletion and Amortization, Property, Plant, and Equipment
Legal Entity
Legal Entity [Axis]
Fair Value Measurements
Fair Value Disclosures [Text Block]
Minimum percentage of shareholder's approval to call for redemption of preferred shares
Required Minimum Shareholder Percentage To Call For Redemption Of Preferred Shares
Required minimum shareholder percentage to call for redemption of preferred shares.
Falikang
Falikang [Member]
Falikang.
Lessee, Operating Lease, Liability, to be Paid, Year Three
2026
Weighted average fair value of stock options granted
Weighted average estimated fair value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Grants in Period, Weighted Average Grant Date Fair Value
Research and Development Arrangement, Contract to Perform for Others, Type
Research and Development Arrangement, Contract to Perform for Others, Type [Domain]
E U Supply And Astellas Agreement
E U Supply And Astellas Agreement [Member]
E U supply and Astellas agreement.
Subsequent Event [Member]
Subsequent event [Member]
Maximum [Member]
Maximum [Member]
Liabilities and Equity
Total liabilities, redeemable non-controlling interests and deficit
Repayments of Secured Debt
Cash paid for transaction costs for senior secured term loan facilities
Rebates and Discounts [Member]
Rebates And Discounts [Member]
Rebates and discounts.
Restructuring and Related Cost, Number of Positions Eliminated, Period Percent
Restructuring plan, expected reduction to workforce, percentage
Total operating lease right-of-use assets
Operating lease right-of-use assets, net
Operating lease right-of-use assets
Operating Lease, Right-of-Use Asset
Prepaid Expense, Current, Total
Prepaid assets
Prepaid Expense, Current
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested, Number of Shares
Shares vested
Supplemental Cash Flow Information [Abstract]
Schedule of Components of Loss Before Income Taxes
Schedule Of Income Loss Before Income Tax Domestic And Foreign Table [Text Block]
Schedule of income loss before income tax domestic and foreign.
FibroGen, Inc. [Member]
Fibro Gen Inc [Member]
FibroGen, Inc.
Investment income in unconsolidated variable interest entity
Disposal Group Including Discontinued Operation Investment Income In Unconsolidated Variable Interest Entity
Disposal group including discontinued operation investment income in unconsolidated variable interest entity.
Net loss per share - diluted
Net loss per share - diluted
Earnings Per Share, Diluted
Leasehold improvements [Member]
Leasehold Improvements [Member]
Development revenue.
Development Revenue [Member]
Total liabilities
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Liabilities
Other investors.
Other Investors [Member]
FibroGen Cayman.
FibroGen Cayman [Member]
Fibro Gen Cayman [Member]
Total liabilities
Liabilities
Common stock voting rights
Common Stock, Voting Rights
Fair Value Hierarchy and NAV
Fair Value Hierarchy and NAV [Domain]
Total current assets
Assets, Current
Net Cash Provided by (Used in) Investing Activities
Net cash provided by investing activities
Issuance of common stock under ATM Program shares
Stock Issued During Period, Shares, New Issues
Unrecognized tax benefits
Beginning balance
Ending Balance
Unrecognized Tax Benefits
Summary of License Revenue and Development Revenue Recognized under Agreement
Contract With Customer Milestone Method Table [Text Block]
Contract with customer milestone method.
Vesting period of stock options
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Period
Cost of goods sold
Disposal Group, Including Discontinued Operation, Costs of Goods Sold
Unamortized issuance costs and transaction costs.
Unamortized Issuance Costs and Transaction Costs
Less: Unamortized issuance costs and transaction costs
Entity Filer Category
Entity Filer Category
General Purchases and Other Programs [Member]
General Purchases And Other Programs [Member]
General purchases and other programs.
Property, Plant and Equipment [Abstract]
Shares issued from stock plans, net of payroll taxes paid
Adjustments To Additional Paid In Capital Shares Issued From Stock Plans Net Of Payroll Taxes Paid
Adjustments to additional paid in capital shares issued from stock plans net of payroll taxes paid.
Future manufacturing clinical regulatory and commercial milestone payments
Future Manufacturing Clinical Regulatory And Commercial Milestone Payments
Future manufacturing clinical regulatory and commercial milestone payments.
Balance
Balance
Equity, Including Portion Attributable to Noncontrolling Interest
Total deficit
Unrecognized tax benefits that would affect effective tax rate
Unrecognized Tax Benefits that Would Impact Effective Tax Rate
Interest and other, net
Nonoperating Income (Expense) [Abstract]
Number of product development obligations
Number Of Product Development Obligations
Number of product development obligations.
Schedule of Other Long-term Liabilities
Other Noncurrent Liabilities [Table Text Block]
Current Fiscal Year End Date
Current Fiscal Year End Date
Loss Contingency, New Claims Filed, Number
Number of complaints filed
Equity, Including Portion Attributable to Noncontrolling Interest [Abstract]
Stockholders' deficit:
Fair Value Assets And Liabilities Measured On Recurring And Nonrecurring Basis [Line Items]
Fair Value, Assets and Liabilities Measured on Recurring and Nonrecurring Basis [Line Items]
Property and Equipment
Property, Plant and Equipment, Policy [Policy Text Block]
Noncontrolling Interests [Member]
Noncontrolling Interest [Member]
Less: Interest
Lessee, Operating Lease, Liability, Undiscounted Excess Amount
ASC 842 [Member]
Accounting Standards Update 2019-01 [Member]
Direct Sales [Member]
Direct Sales [Member]
Direct sales.
Share-Based Payment Arrangement, Noncash Expense, Total
Stock-based compensation
Share-Based Payment Arrangement, Noncash Expense
Outstanding, Aggregate Intrinsic Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Intrinsic Value
Nonconsolidated Investees, Other [Member]
Nonredeemable NCI [Member]
Related Party
Related and Nonrelated Parties [Axis]
Lessee, Operating Lease, Existence of Option to Terminate [true false]
Revenue interest payment
Revenue interest payment.
Acquisition And Variable Interest Entity [Line Items]
Acquisition And Variable Interest Entity [Line Items]
Acquisition and variable interest entity line items.
Beijing Falikang Pharmaceutical Co. Ltd [Member]
Beijing Falikang Pharmaceutical Co Ltd
Beijing Falikang Pharmaceutical Co Ltd [Member]
Beijing Falikang Pharmaceutical Co. Ltd.
Disposal Group, Including Discontinued Operation, Revenue
Product revenue, net
Recognized as Revenue (Discontinued Operations)
Entity Registrant Name
Entity Registrant Name
Available for sale securities in continual unrealized loss position, gross unrealized holding losses
Available for sale securities in continual unrealized loss position, gross unrealized holding losses
Available for sale securities in continual unrealized loss position, gross unrealized holding losses
Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss
Debt Securities, Available-for-Sale, Unrealized Loss Position, Accumulated Loss, Total
Finance leases
Finance Lease, Weighted Average Remaining Lease Term
Dividend received from unconsolidated variable interest entity.
Dividend Received from Unconsolidated Variable Interest Entity
Dividend received from unconsolidated variable interest entity
2027
Revenue Payment Cap Amount Due In Year Five
Revenue payment cap amount due in year five.
Cost of Revenue, Total
Cost of goods sold
Cost of Revenue
Related cost of goods sold
Schedule Of Share Based Compensation Arrangements By Share Based Payment Award [Table]
Schedule of Share-Based Compensation Arrangements by Share-Based Payment Award [Table]
Net Loss Per Share
Earnings Per Share [Text Block]
Maturity date
Debt Instrument, Maturity Date
Entity Emerging Growth Company
Entity Emerging Growth Company
Transaction
Transaction [Domain]
Liability related to sale of future revenues, non-current
Liability Related To Sale Of Future Revenues Non Current
Liability related to sale of future revenues non current.
Recorded Unconditional Purchase Obligation [Table]
Recorded Unconditional Purchase Obligation [Table]
Money market funds [Member]
Money Market Funds [Member]
Basic
Weighted Average Number of Shares Outstanding, Basic
Weighted Average Number of Shares Outstanding, Basic, Total
Consolidation, Variable Interest Entity, Policy [Policy Text Block]
Variable Interest Entity
Variable Interest Entity
Vesting
Vesting [Domain]
Schedule II - Valuation and Qualifying Accounts
SEC Schedule, 12-09, Schedule of Valuation and Qualifying Accounts Disclosure [Text Block]
Finance lease liabilities, non-current
Finance lease liabilities
Finance lease liabilities, non-current
Finance Lease, Liability, Noncurrent
Increase due to prior positions
Unrecognized Tax Benefits, Increase Resulting from Prior Period Tax Positions
Lessee, Operating Lease, Option to Terminate
Lessee, Operating Lease, Option to Terminate
Total interest and other, net
Interest Income (Expense), Nonoperating
Operating Leases
Lessee, Operating Lease, Liability, to be Paid, Fiscal Year Maturity [Abstract]
Income Statement, Balance Sheet and Additional Disclosures by Disposal Groups, Including Discontinued Operations [Line Items]
Disposal Group Including Discontinued Operation Other Liabilities current
Disposal group including discontinued operation other liabilities current.
Operating lease liabilities, current
Expected volatility, maximum
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate, Maximum
Other tax credit carryforwards expiration year
Other Tax Credit Carryforwards Expiration Year
Other tax credit carryforwards expiration year.
Common stock, shares authorized
Common Stock, Shares Authorized
Property and equipment estimated useful life
Property, Plant and Equipment, Useful Life
Sublease income
Sublease Income
Summary of Senior Secured Term Loan Facilities
Schedule of Long-Term Debt Instruments [Table Text Block]
Research and Preclinical Stage Development Programs [Member]
Research And Pre Clinical Stage Development Programs [Member]
Research and pre-clinical stage development programs.
Royalty Revenue [Member]
Royalty [Member]
Proceeds from Issuance of Common Stock
Proceeds from issuance of common stock under employee stock plans
Proceeds from sale of common stock
Concentration Risk Type
Concentration Risk Type [Axis]
Cash and Cash Equivalents [Abstract]
Lessee, finance lease, option to extend the additional lease term
Lessee Finance Lease Option To Extend Additional Lease Term
Lessee, finance lease, option to extend the additional lease term.
Interest on lease liabilities
Finance Lease, Interest Expense
Net unbilled co-development revenue
Supplies Net
Supplies, net.
Net unbilled milestone and co-development revenue
Net contract assets
Equity Method Investment, Nonconsolidated Investee
Equity Method Investment, Nonconsolidated Investee [Axis]
Aggregate considerations received excluding drug product revenue
Collaborative Arrangement Aggregate Consideration Excluding Drug Product Revenue
Amount of aggregate consideration receivable under collaborative arrangement excluding drug product revenue.
RSUs, PRSUs and TSR awards [Member]
RSUs, PRSUs and TSR Awards [Member]
RSUs, PRSUs and TSR Awards [Member]
Deductions, Net
SEC Schedule, 12-09, Valuation Allowances and Reserves, Deduction
Bond and mutual funds [Member]
Bond And Mutual Funds [Member]
Bond and mutual funds.
Level 1 [Member]
Fair Value, Inputs, Level 1 [Member]
Other Liabilities, Noncurrent [Abstract]
Debt Disclosure [Abstract]
Schedule of Activity of Liability Related to Sale of Future Royalties
Schedule of activity of liability related to sale of future royalties [Table Text Block]
Schedule of activity of liability related to sale of future royalties.
Vested and expected to vest, Weighted Average Exercise per Share
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Exercise Price
Warrants to purchase common stock exercised
Class Of Warrant Or Right Number Of Warrants Or Rights Exercised During Period
Class of warrant or right number of warrants or rights exercised during period.
Documents Incorporated by Reference
Documents Incorporated by Reference [Text Block]
Weighted average fair value of stock options granted
Granted, Weighted Average Exercise Price per Share
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Grants in Period, Weighted Average Exercise Price
Disposal Group, Including Discontinued Operation, Accounts Payable, Current
Accounts payable
Lease Termination Settlement Amount One Time Payment
Lease termination settlement amount one time payment.
Lease termination settlement one time cash payment
Financial Instrument
Financial Instrument [Axis]
Outstanding, Weighted Average Remaining Contractual Life
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Remaining Contractual Term
Third party shareholders.
Third Party Shareholders [Member]
Long-term Purchase Commitment, Category of Item Purchased
Long-Term Purchase Commitment, Category of Item Purchased [Domain]
Astellas Japan Agreement [Member]
Astellas Japan Agreement [Member]
Astellas Japan Agreement.
Variable consideration related to payments for milestones considered probable of being achieved
Variable Consideration Payment Received Upon Achievement Of Milestone
Variable consideration payment received upon achievement of milestone.
Revenue payment cap amount due in year three.
2025
Revenue Payment Cap Amount Due In Year Three
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Current Assets, Prepaid Expense and Other Assets
Prepaid expenses and other current assets
Revenue Recognition
Revenue [Policy Text Block]
Proceeds from upfront, non-contingent and non-refundable payments
Proceeds From Upfront Non Contingent And Non Refundable Payments
Represents the total amount of non-contingent, non-refundable, upfront payments included under the collaborative agreement as arrangement consideration.
Share-Based Payment Arrangement [Abstract]
Available-for-sale investments:
OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax [Abstract]
Upfront payment
Upfront Payment
Upfront payment.
Total lease liabilities
Finance Lease And Operating Lease Liability
Finance lease and operating lease liability.
Impairment of Long-Lived Assets
Impairment or Disposal of Long-Lived Assets, Policy [Policy Text Block]
Schedule Of Collaborative Arrangements And Noncollaborative Arrangement Transactions [Table]
Collaborative Arrangement and Arrangement Other than Collaborative [Table]
Roxadustat [Member]
Roxadustat Drug Product [Member]
Roxadustat drug product.
Net cash held
Cash and cash equivalents
Cash and cash equivalents included in assets held for sale
Cybersecurity Risk Role of Management [Text Block]
Transaction price, variable consideration from estimated future co-development billing
Variable Consideration Payment Received From Estimated Future Co Development Billing
Variable consideration payment received from estimated future co-development billing.
Contract assets
Unbilled contract asset
Prepaid Supplies
Estimated Fair Value
Investments
Total investments
Debt Securities, Available-for-Sale
Accounting Policies [Abstract]
Series C [Member]
Series C Preferred Stock [Member]
Summary of Stock Option Transactions
Share-Based Payment Arrangement, Option, Activity [Table Text Block]
Accounting Standards Updates 2014-09 [Member]
Accounting Standards Updates 2014-09.
Accounting Standards Update 2014-09 [Member]
Lease termination, remaining security deposit
Long-Term Line of Credit
Long-Term Line of Credit, Total
Federal and State [Member]
Federal And State [Member]
Federal and state.
Income Tax Disclosure [Abstract]
Increase due to current year position
Unrecognized Tax Benefits, Increase Resulting from Current Period Tax Positions
Restructuring charge.
Restructuring Charge
Restructuring Charge [Policy Text Block]
Manufacturing related milestone payment.
Manufacturing Related Milestone Payments
Manufacturing related milestone payments
Total interest and other, net
Total interest and other, net
Disposal Group Including Discontinued Operation Interest And Other Net
Disposal group including discontinued operation interest and other net.
Total interest and other, net
Foreign government bonds [Member]
Foreign Government Debt [Member]
Effect of Exchange Rate on Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total
Effect of exchange rate change on cash and cash equivalents
Effect of Exchange Rate on Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations
Disposal Group Name [Domain]
Realized loss on sales of available-for-sale securities
Debt Securities Available For Sale Realized Gain Loss Excluding Other Than Temporary Impairments
Debt securities available for sale realized gain loss excluding other than temporary impairments.
Statement [Table]
Statement [Table]
Schedule of Property and Equipment
Property, Plant and Equipment [Table Text Block]
Vested and expected to vest, Weighted Average Remaining Contractual Life
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Weighted Average Remaining Contractual Term
Inventory write-down
Inventory Write-down
Preferred shares issued, price per share
Preferred Shares Issued Price Per Share
Preferred shares issued, price per share.
Transaction price and allocated to performance obligations
Transaction Price Allocated To Performance Obligations
Transaction price allocated to performance obligations.
Preferred stock, shares authorized
Preferred Stock, Shares Authorized
Liability related to sale of future revenues - ending balance
Liability related to sale of future revenues - beginning balance
Liability Related To Sale Of Future Revenues
Liability related to sale of future revenues.
Entity File Number
Entity File Number
Clinical Trial Accruals
Clinical Trial Accrual Policy [Text Block]
Clinical trial accrual.
All other [Member]
All Other [Member]
All other.
Segment and Geographic Information
Segment Reporting Disclosure [Text Block]
Finance Lease, Right-of-Use Asset, Statement of Financial Position [Extensible Enumeration]
Asset-backed securities [Member]
Asset-Backed Securities [Member]
Discontinued Operation, Income (Loss) from Discontinued Operation During Phase-out Period, before Income Tax
Income from operations
Income from operations
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Period Increase (Decrease), Including Exchange Rate Effect
Net increase (decrease) in cash and cash equivalents
Effective Income Tax Rate Reconciliation, Deduction, Percent, Total
Deduction limitation on executive compensation
Effective Income Tax Rate Reconciliation, Deduction, Percent
Revenue:
Revenue from Contract with Customer [Abstract]
Earnings Per Share [Abstract]
Contract with Customer, Asset, after Allowance for Credit Loss, Current, Total
Contract with Customer, Asset, after Allowance for Credit Loss, Current
Contract asset
Nonredeemable non-controlling interests
Nonredeemable Noncontrolling Interest
Increase In Deferred Revenue
Increase In Deferred Revenue [Member]
Increase in deferred revenue.
Stock-based compensation
Deferred Tax Assets, Tax Deferred Expense, Compensation and Benefits, Share-Based Compensation Cost
State tax
Effective Income Tax Rate Reconciliation, State and Local Income Taxes, Percent
Cumulative Revenue
Cumulative Revenue License And Development Revenue Recognized
Total amount of revenue recognized for license and development services under the collaboration agreement as of a given date.
Lease Contractual Term
Lease Contractual Term [Domain]
Statement of Financial Position [Abstract]
Disposal Group, Including Discontinued Operation, Property, Plant and Equipment, Noncurrent
Property and equipment, net
Summary of Equity Method Investment
Equity Method Investments [Table Text Block]
Interest Expense, Total
Interest expense
Interest Expense, Operating and Nonoperating
Schedule of Supplemental Cash Flow Information Related to Leases
Schedule Of Supplemental Cash Flow Information Related To Leases Table [Text Block]
Schedule of supplemental cash flow information related to leases.
IPO [Member]
IPO [Member]
Loss from operations
Operating Income (Loss)
Schedule of Assumptions used to Estimate Fair Value of TSR Awards
Schedule of share based payments award total shareholders return [Table Text Block]
Schedule of share based payments award total shareholders return.
Revenue Recognition, Milestone Method [Line Items]
Expected volatility
Share-Based Compensation Arrangement by Share-Based Payment Award, Fair Value Assumptions, Expected Volatility Rate
Long term Investments Maturity
Long Term Investments Minimum Maturity Period
Long term investments minimum maturity period.
Entity Shell Company
Entity Shell Company
Discontinued Operations, Policy [Policy Text Block]
Discontinued Operations
Professional services
Accrued Professional Fees, Current
Entity Tax Identification Number
Entity Tax Identification Number
Weighted-average discount rate:
Weighted Average Discount Rate [Abstract]
Weighted-average discount rate.
Assets
Assets [Abstract]
Unrecorded Unconditional Purchase Obligation by Category of Item Purchased [Axis]
Fair Value of Financial Instruments
Fair Value of Financial Instruments, Policy [Policy Text Block]
China [Member]
CHINA
Entity Current Reporting Status
Entity Current Reporting Status
Other Revenue [Member]
Other Revenue.
Exercisable, Weighted Average Remaining Contractual Life
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Exercisable, Weighted Average Remaining Contractual Term
Finance Lease, Liability, to be Paid, Year Four
2027
Long-Term Debt, Type [Axis]
Subsequent Events [Abstract]
Valuation Allowances for Deferred Tax Assets [Member]
SEC Schedule, 12-09, Valuation Allowance, Deferred Tax Asset [Member]
Increase (Decrease) in Contract with Customer, Liability
Deferred revenues
Profit share percent
Profit Share Percent
Profit share percent.
Total assets
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Assets
Geographical
Geographical [Domain]
Document Fiscal Year Focus
Document Fiscal Year Focus
Price Adjustment [Member]
Price Adjustment [Member]
Price adjustment.
Acquired in-process research and development asset
Acquired In Process Research And Development Asset
Acquired in process research and development asset.
Disposal Group Including Discontinued Operation Research And Development Expense
Disposal group including discontinued operation research and development expense.
Research and development
Percentage of joint development costs committed to fund
Percentage Of Funding For Costs
Represents the percentage of costs that will be funded by the other party under a collaborative agreement for development costs.
Business combination, recognized identifiable assets acquired and liabilities assumed in-process research and development.
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed In-Process Research and Development
IPR&D assets
Preferred Stock, Value, Issued
Preferred stock, $0.01 par value; 125,000 shares authorized; no shares issued and outstanding at December 31, 2024 and 2023
Disposal Group Including Discontinued Operation Operating Lease Right Of Use Asset Noncurrent
Disposal group including discontinued operation operating lease right of use asset noncurrent.
Operating lease right-of-use assets
Additions
Contract With Customer Liability Additions
Contract with customer liability additions.
Cash And Cash Equivalents And Restricted Time Deposits Policy Policy [Text Block]
Cash and cash equivalents and restricted time deposits policy.
Cash, Cash Equivalents
Disposal Group, Including Discontinued Operation, Liabilities, Noncurrent
Total long-term liabilities held for sale
Long-term liabilities held for sale
Balance in accounts payable and accrued liabilities related to purchases of property and equipment
Capital Expenditures Incurred but Not yet Paid
Lessee, finance lease, initial lease term
Lessee, Finance Lease, Term of Contract
Warrants exercised
Warrants Exercised During Period Value
Warrants exercised during period value.
Schedule of Reconciliation of the Beginning and Ending Amounts of Unrecognized Income Tax Benefits
Schedule of Unrecognized Tax Benefits Roll Forward [Table Text Block]
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations, Total
Total cash and cash equivalents at beginning of period
Total cash and cash equivalents at end of period
Cash, Cash Equivalents, Restricted Cash, and Restricted Cash Equivalents, Including Disposal Group and Discontinued Operations
Total cash and cash equivalents in the consolidated statements of cash flows
Long-term investments
Long-Term Investments, Total
Long-Term Investments
Long-term investment
Proceeds from issuance of common stock under ATM Program, net of commissions
Proceeds from Issuance Initial Public Offering
Business Acquisition
Business Acquisition [Axis]
Collaboration agreement payment
Collaboration agreement payment.
Collaboration agreement payment
City Area Code
City Area Code
Disposal Group, Including Discontinued Operation, Consideration
Aggregate purchase price
Total current liabilities
Liabilities, Current
Accrued Liabilities and Other Liabilities
Accrued and other current liabilities
Disposal Group Including Discontinued Operation Costs And Expenses [Abstract]
Disposal group including discontinued operation costs and expenses.
Operating costs and expenses:
Total inventory
Total inventories
Inventories
Inventory, Net
Equity investments [Member]
Equity Securities [Member]
Finished goods
Inventory, Finished Goods, Gross
Tax at statutory federal rate
Effective Income Tax Rate Reconciliation, at Federal Statutory Income Tax Rate, Percent
Non-contingent upfront payments received
Proceeds From Non Contingent Upfront Payments
Represents the amount of non-contingent upfront payments included under the collaborative agreement as arrangement consideration.
2024
Revenue Payment Cap Amount Due In Year Two
Revenue payment cap amount due in year two.
Discontinued Operation, Name
Discontinued operations name
U.S./RoW and China [Member]
U.S./RoW and China [Member]
United States Rest Of World And China [Member]
United States/Rest of World and China.
Organization, Consolidation and Presentation of Financial Statements [Abstract]
Local Phone Number
Local Phone Number
Eluminex Agreements [Member]
License Agreement With Eluminex [Member]
License agreement with Eluminex.
Eluminex [Member]
Transfers of assets from level 1 to 2
Fair Value Assets Level1 To Level2 Transfer Amount
Fair value assets level1 to level2 transfer amount.
Additional Cash Flow Elements and Supplemental Cash Flow Information [Abstract]
Reconciliation of cash and cash equivalents to the consolidated balance sheets:
Proceeds from sale of future revenues, net of issuance costs
Proceeds From Sale Of Future Revenues Net Of Issuance Costs
Proceeds from sale of future revenues net of issuance costs.
Preferred Stock, Shares Outstanding, Ending Balance
Preferred Stock, Shares Outstanding, Beginning Balance
Preferred stock, shares outstanding
Preferred Stock, Shares Outstanding
Antidilutive Securities Excluded From Computation Of Earnings Per Share [Line Items]
Antidilutive Securities Excluded from Computation of Earnings Per Share [Line Items]
Additional Paid in Capital, Total
Additional paid-in capital
Additional Paid in Capital
Co-development services related to CDK continued over development year
Co Development Services Related To C D K Continued Over Development Year
Co-development services related to CDK continued over development year.
Available for sale securities in continual unrealized loss position, less than 12 months, gross unrealized holding losses
Available for sale securities in continual unrealized loss position, less than 12 months, gross unrealized holding losses
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months, Accumulated Loss
Right-of-use assets cost
Finance Lease Right Of Use Assets Cost
Finance lease, right-of-use assets - cost.
RSUs released and issued net of shares withheld for taxes
Restricted Stock, Shares Issued Net of Shares for Tax Withholdings
Income Tax Authority
Income Tax Jurisdiction [Axis]
Income Taxes
Income Tax, Policy [Policy Text Block]
Commitments and Contingencies Disclosure [Abstract]
Issuance cost
Debt Issuance Costs, Net, Total
Debt Issuance Costs, Net
Convertible promissory note interest rate
Derivative, Fixed Interest Rate
Liability Related to Sale of Future Royalties [Abstract]
Liability related to sale of future royalties.
Amortized Cost
Debt Securities, Available-for-Sale, Amortized Cost
Schedule of Significant Components of Deferred Tax Assets
Schedule of Deferred Tax Assets and Liabilities [Table Text Block]
Astellas [Member]
Astellas [Member]
Astellas.
Operating lease liabilities
Operating lease liabilities, current
Operating Lease, Liability, Current
Transfers of assets out of level 3
Fair Value, Measurement with Unobservable Inputs Reconciliation, Recurring Basis, Asset, Transfers out of Level 3
Finance leases
Right-of-Use Asset Obtained in Exchange for Finance Lease Liability
Variable consideration related to profit share
Variable Consideration Related To Profit Share
Variable consideration related to profit share.
Increase Decrease In Prepaid Expenses And Other Current Assets Related Parties
Prepaid expenses and other current assets from related party
Increase decrease in prepaid expenses and other current assets related parties.
IPR&D Asset [Member]
In Process Research and Development [Member]
Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax, Total
Foreign currency translation adjustments
Foreign currency translation adjustments
Other Comprehensive Income (Loss), Foreign Currency Transaction and Translation Adjustment, Net of Tax
Income Tax Authority
Income Tax Jurisdiction [Domain]
debt interest rate
Interest rate on product development advances
Debt Instrument, Interest Rate, Stated Percentage
Conversion rights, shares issued upon conversion of each preferred share
Convertible Preferred Stock, Shares Issued upon Conversion
Retained Earnings [Member]
Accumulated Deficit [Member]
Payments to Acquire Property, Plant, and Equipment, Total
Purchases of property and equipment
Payments to Acquire Property, Plant, and Equipment
Lease termination settlement amount
Lease Termination Settlement Amount
Lease termination settlement amount.
Operating and finance lease payment obligations
Operating And Finance Lease Payment Obligations
Operating and finance lease payment obligations.
Accrued Liabilities, Current [Abstract]
No Later Than December 31, 2030 [Member]
Payment Period Two [Member]
Payment period two.
Payment Period Two [Member]
Document Transition Report
Document Transition Report
Increase (Decrease) in Other Operating Assets, Total
Other assets
Increase (Decrease) in Other Operating Assets
Percentage of fair value exercise price grant date
Percentage of fair value exercise price grant date
Share-Based Compensation Arrangement by Share-Based Payment Award, Purchase Price of Common Stock, Percent
Lessee, Operating Lease, Liability, to be Paid, Year Two
2025
SEC Schedule, 12-09, Valuation Allowances and Reserves
SEC Schedule, 12-09, Valuation Allowances and Reserves [Domain]
Valuation Approach and Technique
Valuation Approach and Technique [Domain]
Schedule Of Antidilutive Securities Excluded From Computation Of Earnings Per Share [Table]
Antidilutive Security, Excluded EPS Calculation [Table]
Impairment Loss On Debt Securities Available For Sale
Impairment loss on debt securities available for sale.
Impairment loss
U.S. government bonds [Member]
U S Government Bonds [Member]
U.S. government bonds.
Foreign net operating losses not benefitted
Effective Income Tax Rate Reconciliation, Foreign Income Tax Rate Differential, Percent
Exercised, Weighted Average Exercise Price per Share
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Exercises in Period, Weighted Average Exercise Price
Sales Returns [Member]
Sales Returns and Allowances [Member]
Concentration of Credit Risk
Concentration Risk, Credit Risk, Policy [Policy Text Block]
Auditor Firm ID
Auditor Firm ID
Minimum [Member]
Minimum [Member]
Common Stock [Member]
Common Stock [Member]
Share-based Compensation Arrangement by Share-based Payment Award, Compensation Cost [Line Items]
Share-Based Payment Arrangement, Expensed and Capitalized, Amount [Line Items]
Vested and expected to vest, Aggregate Intrinsic Value
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Aggregate Intrinsic Value
Disposal Group, Including Discontinued Operation, Other Assets, Noncurrent
Other assets
Schedule of Drug Product Revenue
Schedule Of Drug Product Revenue Table [Text Block]
Schedule of drug product revenue.
Cash and cash equivalents
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Cash and Equivalents
Investment, Name [Axis]
Unvested, Weighted Average Fair value at Grant, Ending Balance
Unvested, Weighted Average Fair value at Grant, Beginning Balance
Share-Based Compensation Arrangement by Share-Based Payment Award, Equity Instruments Other than Options, Nonvested, Weighted Average Grant Date Fair Value
Additional Paid-in Capital [Member]
Additional Paid-in Capital [Member]
Accounts payable
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Current Liabilities, Accounts Payable
Percentage of revenue sold
Percentage of revenue sold.
Entity Well-known Seasoned Issuer
Entity Well-known Seasoned Issuer
Right-of-use assets cost
Operating Lease Right Of Use Assets Cost
Operating lease, right-of-use assets - cost.
Foreign Currency Translation
Foreign Currency Transactions and Translations Policy [Policy Text Block]
Adjustments to Reconcile Net Income (Loss) to Cash Provided by (Used in) Operating Activities [Abstract]
Adjustments to reconcile net loss to net cash used in operating activities:
Exercised, Shares
Stock Issued During Period Shares Stock Options Exercised Full Year
Stock issued during period shares stock options exercised full year.
Other comprehensive income (loss):
Other Comprehensive Income (Loss), Net of Tax [Abstract]
Income Statement Location
Statement of Income Location, Balance [Domain]
Lessee, Operating Lease, Liability, to be Paid, Year One
2024
Other assets
Other Assets, Noncurrent
Delayed draw term loan two.
Delayed Draw Term Loan Two [Member]
Delayed Draw Term Loan 2
Lease obligations
Deferred Tax Assets, Tax Deferred Expense, Reserves and Accruals, Deferred Rent
Amortization of debt issuance costs and related transaction costs.
Amortization of Debt Issuance Costs and Related Transaction Costs
Issuance costs and related transaction costs, amortised
Value added taxes and other taxes
Accrual for Taxes Other than Income Taxes, Current
Royalty rate against projected net revenues
Royalty Rate On Net Revenue
Implied royalty rate used to find the net present value of future cash flows.
License Acquisition Agreement
License Acquisition Agreement Policy Policy [Text Block]
License acquisition agreement policy.
Conversion Of Subsidiarys Convertible Note Payable
Conversion of subsidiary's convertible note payable.
Conversion of subsidiary's convertible note payable(Note 13)
Debt Securities, Available-for-Sale, Allowance for Credit Loss, Excluding Accrued Interest
Debt Securities, Available-for-Sale, Allowance for Credit Loss, Excluding Accrued Interest, Ending Balance
Debt Securities, Available-for-Sale, Allowance for Credit Loss, Excluding Accrued Interest, Beginning Balance
Available-for-sale debt securities
Schedule of Inventory
Schedule of Inventory, Current [Table Text Block]
FibroGen Beijing [Member]
Fibro Gen Beijing [Member]
FibroGen Beijing.
Income Taxes [Line Items]
Income Taxes [Line Items]
Income taxes line items.
Other current assets
Other Assets, Current
Entity Common Stock, Shares Outstanding
Entity Common Stock, Shares Outstanding
Increase (Decrease) in Accrued Liabilities and Other Operating Liabilities
Accrued and other liabilities
Currency Translation and Other
Contract With Customer Liability Increase Decrease From Current Translation And Other
Contract with customer, liability, increase (decrease) from current translation and other.
Total payments
Revenue payment cap amount
Revenue Payment Cap Amount
Revenue payment cap amount.
Disaggregation Of Revenue [Line Items]
Disaggregation of Revenue [Line Items]
Income (Loss) from Continuing Operations, Per Diluted Share
Loss from continuing operations per share - diluted
Global intangible low-taxed income
Global intangible low-taxed income
Effective Income Tax Rate Reconciliation, GILTI, Percent
Available for sale securities in continual unrealized loss position, less than 12 months, estimated fair value
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, Less than 12 Months
Stockholders' Equity Attributable to Noncontrolling Interest, Ending Balance
Stockholders' Equity Attributable to Noncontrolling Interest, Beginning Balance
Stockholders' Equity Attributable to Noncontrolling Interest, Total
Non-controlling interests
Equity, Attributable to Noncontrolling Interest
Manufacture and Supply of FG - 3246 [Member]
Manufacture And Supply Of FG Three Two Four Six [Member]
Manufacture and supply of FG three two four six.
Basis of Presentation
Basis of Accounting, Policy [Policy Text Block]
Components of Deferred Tax Assets and Liabilities [Abstract]
Finance lease liabilities, current
Finance lease liabilities
Finance lease liabilities, current
Finance Lease, Liability, Current
Domestic
Income (Loss) from Continuing Operations before Income Taxes, Domestic
Common Stock, Value, Issued
Common stock, $0.01 par value; 225,000 shares authorized at December 31, 2024 and 2023; 100,917 and 98,770 shares issued and outstanding at December 31, 2024 and 2023
Collaborative Arrangements and Non-collaborative Arrangement Transactions [Line Items]
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Product revenue from a related party
Product Revenue
Product revenue from a related party.
Amortization of right-of-use assets
Amortization of finance lease right-of-use assets
Finance Lease, Right-of-Use Asset, Amortization
Gain (Loss) on Disposition of Assets
Gain (Loss) on Disposition of Assets, Total
Loss on disposal
Loss on disposal
Assets fair value disclosure
Cash and Cash Equivalents, Fair Value Disclosure
Percentage of tiered royalties receivable.
Percentage of Tiered Royalties Receivable
Percentage of tiered royalties receivable
Accounts payable from related party
Increase Decrease In Accounts Payable From Related Party
Increase decrease in accounts payable from related party.
Fair Values of Financial Assets Measured on Recurring Basis
Fair Value, Assets Measured on Recurring Basis [Table Text Block]
Charged to Other Accounts - Liabilities and Equity
SEC Schedule, 12-09, Valuation Allowances and Reserves, Additions, Charge to Other Account
Transfer price true up
Transfer Price True Up
Transfer price true up.
Operating Lease, Liability, Total
Present value of lease liabilities
Operating lease liability
Operating Lease, Liability
Measurement Frequency
Measurement Frequency [Axis]
Schedule of Accrued and Other Current Liabilities
Schedule of Accrued Liabilities [Table Text Block]
Deferred Tax Assets, Operating Loss Carryforwards, Total
Federal and state net operating loss carryforwards
Deferred Tax Assets, Operating Loss Carryforwards
Other-than-temporary impairment loss
Other-than-temporary Impairment Loss, Debt Securities, Available-for-Sale
Commitments and Contingencies
Commitments and Contingencies (Note 12)
Schedule of Activity of Liability Related to Sale of Future Revenues
Schedule Of Activity Of Liability Related To Sale Of Future Revenues [Table Text Block]
Schedule of activity of liability related to sale of future revenues.
Schedule Of Entity Wide Revenue By Major Customers By Reporting Segments [Table]
Schedule of Revenue by Major Customers, by Reporting Segments [Table]
Income before income taxes
Discontinued Operation, Income (Loss) from Discontinued Operation, before Income Tax
Income before income taxes
Available for sale securities in continual unrealized loss position, 12 months or more, gross unrealized holding losses
Available for sale securities in continual unrealized loss position, 12 months or more, gross unrealized holding losses
Debt Securities, Available-for-Sale, Continuous Unrealized Loss Position, 12 Months or Longer, Accumulated Loss
Impairments Of Investments
Impairments of investments.
Impairment of investment
Maximum additional future clinical, regulatory, and commercial milestone payments
Maximum Additional Future Clinical Regulatory And Commercial Milestone Payments
Maximum additional future clinical regulatory and commercial milestone payments.
Diluted
Weighted Average Number of Shares Outstanding, Diluted
Weighted Average Number of Shares Outstanding, Diluted, Total
Summary of Significant Accounting Policies
Significant Accounting Policies [Text Block]
Entity Wide Revenue Major Customer [Line Items]
Revenue, Major Customer [Line Items]
Finance Lease, Liability, Noncurrent, Statement of Financial Position [Extensible Enumeration]
Accounts Receivable, after Allowance for Credit Loss, Current
Accounts receivable, net ($6,079 and $12,088 from related parties)
Accounts receivable from related parties
Accounts receivable, net
Research and Development Arrangement, Contract to Perform for Others, Type
Research and Development Arrangement, Contract to Perform for Others, Type [Axis]
Vested and expected to vest, Shares
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Vested and Expected to Vest, Outstanding, Number
Total future lease payments
Lessee, Operating Lease, Liability, to be Paid
Increase (Decrease) in Inventories, Total
Inventories
Increase (Decrease) in Inventories
Cybersecurity Risk Management Third Party Engaged [Flag]
Lessee, finance lease, additional lease expiration period
Lessee Finance Lease Additional Lease Expiration Period
Lessee, finance lease, additional lease expiration period.
Concentration Risk Benchmark
Concentration Risk Benchmark [Domain]
Operating costs and expenses:
Operating Costs and Expenses [Abstract]
Finance Lease, Liability, Total
Present value of lease liabilities
Finance lease liability
Finance Lease, Liability
Entity Small Business
Entity Small Business
Segment Reporting Information [Line Items]
Segment Reporting Information [Line Items]
Bulk Drug Product
Bulk Drug Product [Member]
Bulk drug product.
Bulk Drug Product [Member]
Manufacture and Supply of Roxadustat [Member]
Manufacture And Supply Of Roxadustat [Member]
Manufacture and Supply of Roxadustat.
Cybersecurity Risk Management Processes for Assessing, Identifying, and Managing Threats [Text Block]
Segment Reporting, Disclosure of Entity's Reportable Segments [Abstract]
Debt Disclosure [Text Block]
Senior Secured Term Loan Facilities
Billed Contracts Receivable
Revenues, Total
Revenue recognized
Revenues
Contract with Customer, Asset, Cumulative Catch-up Adjustment to Revenue, Modification of Contract
Cumulative catch-up net adjustment
Acquired in-process research and development expenses.
Acquired In-process Research and Development Expenses
Acquired in-process research and development expenses
Recorded Unconditional Purchase Obligation, to be Paid, Year Two
Purchase obligations due 2026
Maximum Research and Development and Regulatory Milestone Payments Receivable
Maximum Research and Development and Regulatory Milestone Payments Receivable
Maximum R&D and regulatory milestone payments receivable
Disposal Group, Including Discontinued Operation, Liabilities, Current
Total current liabilities held for sale
Current liabilities held for sale
Rent increase commencement year first option
Scheduled Rent Commencement Year Option One
Rent commencement year option one.
Co-promotion expenses
Co Promotion Expenses
Co-promotion expenses.
Weighted-Average Offering Prices Per Share
Weighted-average offering prices per share
Weighted-average offering prices per share
Investment income in unconsolidated variable interest entity
Investment Gain Loss In Unconsolidated Variable Interest Entity
Investment (gain) loss in unconsolidated variable interest entity.
Leases
Leases Disclosure [Text Block]
Leases.
RSUs, PRSUs and TSR awards [Member]
Restricted Stock Units Perfomance Based Restricted Stock Units and Total Shareholders Return [Member]
Restricted stock units perfomance based restricted stock units and total shareholders return.
Business Combination, Recognized Identifiable Assets Acquired and Liabilities Assumed, Net
Net identifiable assets, liabilities and non-controlling interests
Net identifiable assets, liabilities and non-controlling interests
Accumulated amortization
Operating Lease Accumulated Amortization
Operating lease, accumulated amortization.
Accrued litigation settlement
accrued litigation settlement.
Accrued Litigation Settlement
Expired, Weighted Average Exercise Price per Share
Share-Based Compensation Arrangements by Share-Based Payment Award, Options, Expirations in Period, Weighted Average Exercise Price
Cash paid for amounts included in the measurement of lease liabilities:
Cash Paid For Amounts Included In Measurement Of Lease Liabilities [Abstract]
Cash paid for amounts included in the measurement of lease liabilities.
Net accretion of premium and discount on investments
Accretion (Amortization) of Discounts and Premiums, Investments
Accrued interest for finance lease liabilities
Increase Decrease In Accrued Interest For Finance Lease Liabilities
Increase (decrease) in accrued interest for finance lease liabilities.
Accounting Policy [Table]
Accounting Policy [Table]
Accounting policy.
Financing activities
Net Cash Provided by (Used in) Financing Activities [Abstract]
Outstanding, Beginning Balance, Weighted Average Exercise Price per Share
Outstanding, Ending Balance, Weighted Average Exercise Price per Share
Share-Based Compensation Arrangement by Share-Based Payment Award, Options, Outstanding, Weighted Average Exercise Price
Weighted Average Number of Shares Outstanding Reconciliation [Abstract]
Weighted average number of common shares used to calculate net loss per share
Disposal Group, Including Discontinued Operation, Accounts, Notes and Loans Receivable, Net
Accounts receivable, net
Percentage points deducted to reference rate to compute effective interest rate
Loans Receivable, Basis Spread on Variable Rate
Deferred Tax Liabilities Non Deductibale Accrued Expenses
Deferred tax liabilities non deductibale accrued expenses.
Non-deductible accrued expenses
Non-deductible accrued expenses
Liability related to sale of future revenues current.
Liability Related To Sale Of Future Revenues Current
Current portion of liability related to sale of future revenues
State [Member]
State and Local Jurisdiction [Member]
Operating leases
Right-of-Use Asset Obtained in Exchange for Operating Lease Liability
Measurement Frequency
Measurement Frequency [Domain]
Conditions of payment of interest, convertible promissory note
Long-Term Debt, Contingent Payment of Principal or Interest
Nature of Operation, Product Information, Concentration of Risk [Table]
Credit Concentration Risk [Member]
Credit Concentration Risk [Member]
Less: Valuation allowance
Deferred Tax Assets, Valuation Allowance
Work-in-progress
Inventory, Work in Process, Gross
Level 3 [Member]
Fair Value, Inputs, Level 3 [Member]
Operating leases
Operating Lease, Weighted Average Remaining Lease Term
Option vesting term
Share-Based Compensation Arrangement by Share-Based Payment Award, Award Vesting Rights
License and Development [Member]
License And Development [Member]
License and development.
Subsequent Events [Text Block]
Subsequent Event
Reclassified to accrued liability / accounts payable
Contract With Customer Liability Reclassified to Accrued Liability
Contract with customer liability reclassified to accrued liability.
Employee stock purchase plans [Member]
Share-Based Payment Arrangement [Member]
Gain (Loss) on Termination of Lease
Gain on lease termination
Sales To Falikang
Sales To Falikang [Member]
Sales to Falikang.
Sales To Falikang [Member]
OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax, Total
Change in unrealized gain or loss on investments
OCI, Debt Securities, Available-for-Sale, Gain (Loss), after Adjustment and Tax
Cybersecurity Risk Management Positions or Committees Responsible [Flag]
Accounts payable
Accounts Payable, Current, Total
Accounts Payable, Current
Proceeds from Issuance of Secured Debt
Proceeds from senior secured term loan facilities, net of issuance costs
Astra Zeneca
Astra Zeneca [Member]
AstraZeneca.
Currency translation adjustment
Translation Adjustment Functional to Reporting Currency, Net of Tax, Ending Balance
Translation Adjustment Functional to Reporting Currency, Net of Tax, Beginning Balance
Translation Adjustment Functional to Reporting Currency, Net of Tax
Total operating costs and expenses
Costs and Expenses
Percentage of royalty payment on global net sales
Percentage of royalty payment on global net sales.
Disposal Group, Including Discontinued Operation, Liabilities [Abstract]
Liabilities
Weighted-average remaining lease term (years):
Weighted Average Remaining Lease Term [Abstract]
Weighted-average remaining lease term.
Accounts Receivable, Allowance for Credit Loss, Ending Balance
Accounts Receivable, Allowance for Credit Loss, Beginning Balance
Reductions to gross accounts receivable
Accounts Receivable, Allowance for Credit Loss